Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62810	Protriptyline	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	176	KLF10; AFF4; IRF1; GTF2I; MTA1; IKZF5; NPAS1; SOX10; ZNF16; SIX6; TXNIP; ZNF282; DBP; NR0B1; SERTAD2; BARX2; SATB1; GABPA; CIITA; HOXC10; TSC22D3; TAF1A; ING2; ZBTB32; FOSL1; RAD21; CREG1; VAX2; JARID2; MAPK8IP1; LZTS1; SAP30; RBBP8; NKX3-2; NHLH2; BCL11B; BHLHE40; KLF4; ZBTB1; HOXB13; RUVBL2; KAT8; LHX1; ZNF415; SMAD6; AEBP1; SIX1; ZNF302; VGLL1; SALL1; SIX2; BLM; ZNF219; ZNF460; SRF; PITX1; ATF6; ATF4; PURA; NKX2-2; PAX5; ZNF329; SSBP2; TBX2; MAFG; ZNF528; CREB3L1; NFATC3; NFYA; NFIC; HOXC6; AHR; POU4F1; SMAD9; TAF12; HMGN3; ELF3; TSC22D2; BRPF1; MAX; MED20; APEX1; EMX2; CAPN15; WHSC1; FOXE1; BAZ1B; NR1D2; PPP1R13L; CD3D; ZNF266; UBE2I; DDIT3; ZNF131; PCGF2; SKI; PHIP; ZNF14; FOXA2; TAF9B; ID4; EHMT2; TEAD4; TBX21; YBX2; PAX9; IKBKAP; EZH2; HSF2; SOX4; BATF; MAFF; SMARCA1; HOXD10; ZZZ3; PCGF1; NONO; EYA2; ZNF516; CITED2; MED21; CCDC59; RXRA; CUX1; PEG3; HEY1; TMF1; WWTR1; STAT1; HES1; TAF9; SMAD5; EPAS1; MED1; GATA2; HEY2; TFEB; ING3; CCNA2; ZBED2; BHLHE41; NCOA4; TFDP2; HIPK3; FOXC1; PSIP1; REPIN1; ZEB1; DNMT3B; COPS2; ZNF107; ZMIZ1; HMGA2; ETV5; ZNF146; RREB1; CARHSP1; SOX11; ABL1; LEF1; TOX; CDK7; TRIM16; BCL3; TULP4; MSX1; ISL1; STAT5B; LOXL2; CITED1; HLF; TWIST1; HIC2; TCEA2; HMG20B; ERG
Down-regulation	150	KDM5A; LDB1; HMGB3; TFDP1; ZNF430; TLE1; ZBTB7A; ARNTL; SUZ12; JUP; CNOT6; ATN1; SP100; ZNF24; ZNF44; PBXIP1; ARID5A; TGFB1I1; BAZ2B; THAP11; CEBPZ; CCNT1; CHD4; HDAC3; IRX4; SUPT5H; KAT2A; FOSB; FOS; CNOT1; INSR; RNF6; NR1H2; ETV6; MAF; ZNF354A; POLR3C; CDK9; ZNF189; ING4; THAP7; TOX3; CALCOCO1; KLF1; SPI1; FOXJ1; NFKBIB; CAMTA2; CBFB; PSMC3; KMT2A; TRIB3; ZNF215; ZNF512B; NFATC4; PREB; GTF3A; PRDM14; HLX; ARID4B; BRD4; CENPF; ZNF35; ZNF532; SP110; MXI1; CRK; HMGA1; TCF3; FOXF2; E2F2; TRPS1; ZNF646; USP16; ZNF148; UBP1; AR; MED17; VDR; TCF15; CDK8; ELK3; ARID5B; KDM2A; HDGF; ZMYM2; ERBB2; MXD4; OLIG2; SF1; WDR77; IL16; NFIB; KDM5C; HOXB2; NPAT; HDAC7; CCNE1; ARL2BP; MED15; MYCL; ASCL1; SREBF1; ZFP36L2; TP53; CREBL2; REL; SETDB1; CDK2; TFCP2L1; CEBPA; PBX3; TRIM32; SOHLH2; ID2; NAB2; ZKSCAN1; PFDN5; RFX5; DNAJC1; BIRC2; PSPC1; BNC2; MLLT10; SNAI2; NFYC; NANOG; TRIP6; SOX9; BMI1; WWC1; CREB3L2; ESR1; SMAD3; ZNF544; DAXX; TBX3; BASP1; NRIP1; TCF4; NR4A2; FLNA; FOXO1; KAT6B; USP22; SUB1; ZNF91; TSC22D1; IRF8; TOB1