Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62796	Trimethobenzamide	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	KDM5A; RUNX3; HOXC10; ZNF589; YY1; BCL11B; SOX13; SMAD1; SAFB2; MTA1; EP300; HMGN3; CTCF; JUP; FOXM1; KMT2D; MKL1; SP140; NFKBIB; LMCD1; VGLL1; DACH1; SOX11; UBE2B; ZNF335; IL16; SF1; RARA; E2F5; PRDM4; NCOA2; RREB1; ZEB2; ZNF227; AES; MXI1; HMGB3; MYT1; FOXJ3; SERTAD2; CREB1; HMBOX1; DLX4; ZNF211; JUND; IRF7; TWIST1; CNOT6; IRX5; CHD3; ST18; ZNF573; IRF1; SMARCA1; PITX2; BLZF1; PSMC3; NRBF2; EGR4; INSM1; ERBB4; HLTF; ZBTB24; PRDM10; ZSCAN32; STAT4; DDX17; DBP; CASZ1; MYCN; OVOL2; DMTF1; MEOX1; RNF14; PIAS4; PAX5; EZH1; NFIC; CBFA2T3; NR2F6; PPRC1; LHX3; TAF9B; SMAD7; PRDM2; ARID3B; ID4; ZNF587; BLM; COPS5; ZNF224; CAMTA1; MEOX2; ZNF410; TLE2; MXD4; BBX; KAT2B; IRF9; TRIM32; RXRA; TFDP2; SCMH1; HOXB6; RBBP7; INSR; VDR; ZNF177; SOX9; KLF6; FOXO3; BARX1; MYB; ESRRG; TULP4; ZNF266; TCF21; URI1; IRF4; ZNF512B; YWHAB; HR; CREBZF; TERF1; AEBP1; NFE2; ZNF91; CREB3L2; NKX2-2; BCL11A; NFYC; IRF2; BHLHE41; BHLHE40; BRD8; MEF2C; ZMIZ1; MSX1; HMG20B; RFX5; NCOR2; ZNF721; MYBL1; CHD7; SPEN; ID2; EGR2; CTNNB1; MEIS2; TOX; BRD2; TBL1X; HOXB2; FOS; LEF1; SCAND1; MECOM; TOB1; TCEA2; PITX1; PBX1; CDK7
Down-regulation	178	HOXA5; ZNF423; YBX3; NFE2L2; ZBED4; STAT5A; WIZ; DEK; TCF25; NAB1; TRIM29; SSRP1; HIF1A; TFAP4; MTDH; YEATS2; SATB2; IKZF2; STAT6; COPS2; MYC; SP100; ELF5; ARID4A; MITF; YBX1; NR1H4; CDK8; MED13; HMGA1; MBD2; ECD; NKRF; ELK1; GTF2A2; KAT7; DNAJC2; CNOT1; SOHLH2; AGO2; CREG1; TBP; ZNF267; FOXO4; VGLL4; CRTC1; THAP10; NFE2L1; ZKSCAN8; HEY1; TRIP6; RORC; CCDC59; RNF111; POLR3C; ZBTB43; SMARCA5; SMARCD3; MXD3; HOXA4; UBTF; XBP1; GABPA; ZNF354A; NFAT5; TFAM; MAFF; TFAP2C; EZH2; ELK4; ELF2; HIRA; TADA3; TCEB2; UBE2I; TTF2; MDM4; GCFC2; MED4; RFX7; RBBP8; NR1H3; RRN3; MTF2; STAT3; ID1; E2F3; THAP11; NCOA4; RBFOX2; CCNA2; THAP4; ZFHX4; MDM2; USP22; LIN28A; CERS6; BAZ1A; ZNF629; OLIG2; LOXL2; CCNH; DEAF1; TLE1; ZBTB38; BCL6; SAP30; SMAD3; CEBPZ; FOXF2; ZZZ3; GTF2IRD1; TP53; REXO4; ACTL6A; PMS1; ZNF331; SND1; MKL2; HBP1; BNC2; KAT6A; HOXD11; CBX6; ZNF22; HSBP1; FHL2; TEAD4; NPAT; PDLIM1; ERBB2; NRIP1; DNMT3B; NPAS2; SSBP2; RELA; NUP62; ZNF443; RUVBL2; JUNB; NFIB; TMF1; NFE2L3; TRIM16; ZNF273; BRWD1; KAT6B; PTTG1; ELF3; ZHX2; NELFB; ZFPM2; DRAP1; ISL1; EMX2; TSC22D1; PSIP1; ID3; FOSL2; STAT1; NR2F2; TGIF1; TOX3; BIRC2; ABL1; ATF3; STAT5B; FLNA; NR4A2; OSR2; ERG; NKX3-1; TP63; HTATIP2; SATB1; BASP1; HES1; RELB