Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62792	Guanfacine	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	158	MNAT1; CREB1; NR2F6; MYCL; INSR; ZNF589; HOXD1; HDAC6; ASCL1; JUP; INSM1; IRX5; TTF2; VPS72; E2F8; ONECUT2; TAF1A; SIX1; PEX14; IRF1; ACTL6A; HIVEP1; ZNF257; RAD21; PBX3; NR5A2; HMGB3; SERTAD2; ARNT; MECOM; OVOL2; NHLH2; NR1I2; SOX10; CBFA2T3; HMG20A; ATF6; IRF4; PRKDC; LMCD1; NCOA1; HOXD3; DDX5; ZNF682; SMAD6; BLM; PLAGL2; ZNF711; SOX11; SOX18; TSG101; CAMTA1; ARNTL2; NEUROD1; EBF2; ZNF552; BLZF1; ZNF302; FOXJ3; MYT1; MYCN; FLI1; SIX3; YEATS4; KAT2B; BRIP1; ZSCAN9; NFE2L3; GATA6; ZBTB11; ZNF492; WDHD1; ZSCAN18; ZFP69B; CERS4; ZNF91; BRCA2; MYBL2; PBX1; PAWR; MEOX1; ZIC3; ZBED2; CHD7; HABP4; E2F5; NKX2-1; ZNF329; ZNF426; ZNF24; ETS1; KDM5C; SHOX2; ZNF93; SNAI2; MED24; EWSR1; HOXB13; ARID3B; MED14; FOXC1; RBL1; PARP1; ZNF232; SMAD2; CERS6; CUX2; THRAP3; IRF7; GFI1; ZMYND8; FOXN3; SUZ12; DDIT3; GATA2; WWP1; MYBL1; TBL1XR1; PKNOX2; ISL1; SMARCC2; PLAG1; NKX2-2; ZNF107; L3MBTL1; IRF8; ZNF587; MSX1; DBP; TOX; FOXE1; URI1; TFDP2; PMF1; LZTS1; TSC22D2; ERBB4; ZMYM2; TAF9B; SPIB; ID4; POU2AF1; JARID2; ZBTB20; TERF1; ETS2; NFATC3; MEIS2; STAT1; ERG; RXRA; KLF9; TCEA2; ZBTB38; HOXB7; DACH1; PLAGL1; WT1
Down-regulation	219	NFE2L2; TCF25; ZNF12; ZFP36L1; TGFB1; ZNF32; SP100; ETV4; SMARCD3; MTDH; STAT5A; HMGXB3; HCFC1; JUN; MAFF; MED23; ERCC3; ETV5; UBE2B; HMGA1; HOXA5; TAF12; ZNF576; ARID5A; NR2E1; ZNF226; ZNF394; TGIF1; TFDP1; ITGB3BP; MED15; CREG1; THAP7; NKRF; APEX1; GCFC2; ZNF263; RUVBL2; PA2G4; FOXK2; NPM1; DNMT1; YBX3; EMX2; RBPJ; DEAF1; ZNF212; SALL1; PEX2; PCGF2; CNOT1; NFKBIB; CEBPZ; PAX8; TRIM28; LYL1; HDAC3; UBP1; HSF1; CTCF; TRIP6; FOXO4; ZNF3; STAT6; MKL2; VGLL1; EED; HIPK2; ZBTB14; CNOT3; CIC; CBX3; MBD3; MEIS1; ZNF148; TCEB2; TRIM22; RNF111; MYCBP; ZMIZ1; ZNF324; NEDD8; HIPK1; SOX9; CITED2; PQBP1; BAZ1A; LITAF; CEBPA; XBP1; AR; RNF10; EYA2; CXXC1; THAP11; ZBED1; CARHSP1; BRD4; GON4L; BRD7; HOXB2; KAT8; TLE4; MBD2; PFDN5; PCGF1; AES; FLNA; C1QBP; SIRT7; ZNF23; KAT5; TBPL1; DNAJC2; PEG3; UBE2I; MAF; HDAC2; ARL2BP; MAX; ZNF423; TBP; PHF8; WWTR1; ESR1; LPIN2; PMS1; SMARCA2; USP16; KAT2A; LDB1; ZNF45; BIRC2; ZFP36L2; KLF1; CHD8; HOXD11; MYC; SUMO1; SP3; KAT6B; GMNN; ZNF124; FOXJ1; PHF1; SAP30; VGLL4; FOXF2; DAXX; ZNF580; AIP; E2F2; MLX; HIC2; AHR; RB1; MTF2; NRIP1; SP140L; AFF1; MITF; TRPS1; RERE; NFYC; CNOT2; SSBP2; ZNF273; CRYM; NCOA4; TFAP2C; PCBD1; CCNC; HMGB2; SALL2; SMARCD2; ZNF84; NR2F1; SMARCA1; RBL2; ABL1; CCNA2; MAZ; ELK3; RHOA; FOXG1; NFE2; NANOG; TBL1X; ZBTB18; ELF4; ZEB1; RREB1; GATA3; HDAC4; ELF3; RFX5; USF2; NFAT5; PTRF; TSC22D1; EZH2; ZFPM2; TOB1; SIAH2; EHF; NPAS2; HTATIP2; NR2F2; ZNF544; BRD2; DRAP1; HES1; HEY1; TBX3; RELB; BHLHE41; KDM5D; MAFB; BASP1