Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62787	Proguanil	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	CTBP2; TDRD3; SMAD1; SAP18; ZNF131; HMGB1; THAP4; NFKB2; RNF10; LMCD1; CARM1; NFIC; MYRF; TCF12; CDK8; ZNF12; MLXIP; HOXD10; NFE2L1; HOXB13; KAT7; ZMYM2; ZEB2; NCOA3; BHLHE40; KLF6; ATF4; EYA2; TAF10; TRIM28; SFPQ; ZNF217; MLX; PQBP1; RUVBL2; SAP30; SUPT3H; LDB1; BRD4; TP53; PCGF1; SSBP2; SMAD6; AEBP1; WWC1; SIX3; C1QBP; SMARCC2; ID2; ZNF91; TFCP2L1; CRY1; BRD2; HMGA1; PTRF; MITF; PSPC1; COPS2; ZMYND8; AFF1; KDM5D; YBX3; ZBTB16; TRIM22; ZHX2; KLF2; KAT6B; PSIP1; ID1; OSR2; MYB; CUX1; BIRC2; CITED2; RFX5; BBX; ERBB2; ZKSCAN1; TXNIP; MSX1; USP22; ELK3; NKX3-1; SCAND1; NFKBIA; CRK; CCNA2; CDK7
Down-regulation	85	TRIB3; CEBPD; ZSCAN31; GTF2I; TCERG1; RCOR1; ZNF141; MTDH; MED21; SHOX2; ZNF43; NCOA2; AR; TAL1; VDR; ACTL6A; TAF9B; ZNF10; MEIS1; HIVEP1; ZNF117; MKL2; LHX2; NR2F1; TCEA1; FOXM1; KDM5C; ZNF273; NRBF2; ZNF529; HDAC2; HOXD1; WWTR1; PLAG1; EGR2; AGO2; OLIG2; NFATC1; BRWD1; ZMIZ1; ZNF75D; NAB2; LPIN2; PKNOX2; ARID4B; ZNF107; ZNF589; ZNF623; HLX; NFE2; FOXF1; BACH1; HIPK3; GATA6; CAMTA2; PHF20; RBFOX2; IRF4; EGR3; CUX2; TRIM24; FOXF2; NKX2-1; PEG3; IFI16; ATF3; KLF4; LITAF; DAXX; ID4; ZIC1; MEF2C; SMAD3; SATB1; PLAGL1; ARID5B; BCL3; HES1; PITX1; HHEX; HMG20B; LOXL2; TRPS1; MAFB; BASP1