Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62781	Rofecoxib	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	165	SERTAD2; MNAT1; RUNX3; ZNF589; DLX4; JUP; ONECUT2; CEBPD; VGLL1; MED12; GFI1; IRX5; HOXA1; IRF1; ARID3B; ZBTB40; BCL10; SOX21; ZNF529; KMT2D; EPAS1; NRBF2; BCL11B; ZNF165; TLX3; NOCT; TCF7; KLF13; ZBTB11; PRDM2; RAD21; MYB; SMAD7; SOX11; ATF6; DBP; INSR; WNT4; RARG; LEF1; ERG; FOXI1; PITX2; RNF10; SOX18; E2F3; YBX2; EGR4; GATA3; NFYB; PLAG1; DDX5; VDR; NLK; PML; SUZ12; CHD1; TGFB1; ZNF778; SP140; EP400; ZNF184; TSC22D2; NKX2-2; TCF4; ELF4; PBX2; AEBP1; RUNX1; E2F5; ZIC1; ZNF24; TEAD4; ZNF302; FOXJ3; IRF5; ZBTB1; FOXD1; PLAGL2; IKZF1; CDK9; ZNF281; HIC2; FLI1; HIPK1; EZH1; PRMT2; ABT1; ZNF131; SCMH1; TERF1; VGLL4; GATA2; DLX5; CCNE1; HIVEP1; NR1D2; WWP1; CDK8; PURA; MYBL1; CHD7; BATF; ZNF329; HMGN3; PRRX2; IRF4; CBFA2T3; CRY1; GATA6; TCF7L1; HIRA; MNDA; BLM; FOXC1; ZNF211; BMI1; SPEN; PAWR; CAMTA1; DDIT3; INSM1; ID2; LPIN2; ZHX2; NFE2L3; RNF6; SMAD2; DNAJC2; BACH1; CREB1; CCDC59; RSF1; TCF3; STAT4; URI1; BRD2; LZTS1; HMGB3; SSX1; ZNF117; ZNF587; SOHLH2; FOS; POU4F1; BBX; YWHAB; MSX1; ERBB4; ENO1; TOX; MEF2A; MEIS2; CCNC; DACH1; CD3D; CBFA2T2; DAXX; STAT1; PBX3; HOXB7; BHLHE41; WT1; PLAGL1; TCEA2
Down-regulation	173	CNOT1; THAP10; PCGF2; APEX1; ZNF423; NFE2L2; CHD8; TCF25; AR; BAZ1A; ETV4; STAT6; CERS4; MEIS1; ZNF12; NEDD8; JUN; ZFP36L1; MITF; GTF2A2; CREG1; TCEA1; TBX3; CEBPB; ERCC3; SND1; HOXA5; THAP7; THAP11; JAK2; SOX9; LITAF; ZNF133; MEOX1; EYA2; ZNF426; AHR; ZNF205; TLE4; PTTG1; RBPJ; TCEB2; SALL1; XBP1; FOXO4; ARL2BP; RCOR3; TFAM; ARID1A; ZMIZ1; CREB5; MEOX2; NFIB; RRN3; SREBF2; MAF; NFE2L1; TGFB1I1; TOX4; SPIB; FOXF1; TULP3; SAP18; ID1; ZNF430; CCNH; FOXK2; SMARCD3; TFAP2C; SPDEF; EZH2; DRAP1; TP63; HMGXB4; PSIP1; EHF; PSMC3IP; CEBPZ; ZBED1; RFX7; IKBKAP; ZNF85; ARID4B; APBB1; SMARCC1; TEAD1; PPARGC1A; PHIP; CERS6; HOXB2; IRF9; KAT6A; ALX1; YBX3; KLF9; KLF5; HSBP1; MKL2; SSBP2; EDF1; SMAD3; NFKB1; EMX2; TOX3; ABL1; NR4A1; BRD7; HOXB5; HLF; FLNA; ELK4; TXNIP; SALL2; ZNF248; PREB; HHEX; SIX2; ZNF551; KAT6B; NKX3-1; HOXB6; ZNF148; HDAC2; MYCN; ZNF239; HES1; NR4A2; ISL1; NELFB; ERBB2; TP53; PAX5; COPS2; PBX1; FOXF2; ZNF331; HDAC9; NR2F2; PCBD1; LOXL2; PITX1; NCOA4; MED17; ETV5; TRIM24; CBX6; TSC22D1; ZBTB16; ZNF544; SOX4; CCNA2; ARID5B; NPAS2; HTATIP2; FHL2; SATB1; TRIM16; SUPT4H1; HMG20B; NANOG; RBPMS; BIRC2; ZBTB18; ZBTB20; BASP1; BCL3; ID3; TBL1X; NR2F1; PEG3; ATF3; RELB; KDM5D