Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62766	Methantheline	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	MNAT1; NR3C1; CREB1; CNOT6; HDAC6; CTBP2; ZFX; IFI16; SIX1; MYBBP1A; RXRA; INSM1; NCOA1; KLF11; ZBTB11; IRF1; CHD7; SOX11; FOXG1; NR4A3; BLZF1; TRIM29; TBX21; KAT2B; EYA1; WWP1; TDP2; SIX2; ERBB4; BRD3; MXI1; ACTL6A; HIVEP1; ZEB1; SNAI2; ATF2; CRYM; PRMT2; STAT4; TFEB; MYCL; DEK; NFYB; NKX3-1; DMTF1; KLF13; MYBL1; ZNF264; SMAD4; TP63; RUNX1; ZIC1; ZMYM2; KLF10; SFMBT1; CRY1; BTG1; ZBTB38; HMGB3; ETS1; FOXC1; PTTG1; MED24; CBFB; PHIP; PBX3; RNF138; CDK2; BAZ1B; ATF3; YBX3; CBFA2T2; ARID5B; SP140L; ZNF232; RBFOX2; NKX2-2; DACH1; HDGF; HDAC9; TERF1; SPDEF; FOS; TCF7L2; IRF8; SHOX2; MEIS2; MAFB; ZNF91; FOXF2; THAP11; IRF6; FOXF1; HMG20B; KLF9; ABL1; HES1; BASP1; TRPS1; TCEA2
Down-regulation	67	SOX9; GATA6; HMBOX1; MAFG; SATB2; GLI2; DRAP1; ZMYND8; ATF4; ETV4; TP53; SREBF1; RBBP4; BRF2; NEDD8; TRIM22; NANOG; ZNF3; RUVBL2; ARID3A; PBX2; ZFHX4; TRIM28; GTF3A; HEY2; ELF1; MAF; ASH2L; NPM1; LIN28A; ID2; MAGED1; TRIM24; CEBPA; ZNF443; PURA; TLE4; YAP1; LPIN2; SMAD3; JUND; KAT6B; EMX2; BNC2; DNMT3B; LEF1; RBBP7; YWHAB; FHL2; NCOA4; RBPMS; KLF2; TSC22D1; CCNA2; RFX5; ZBTB18; TBX2; CALR; BIRC2; TBL1X; TWIST1; SATB1; ESR1; HTATIP2; EZH2; RELB; PEG3