Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62765	Thiotepa	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	TBP; HOXC10; NFX1; HOXD1; ZNF589; ZNF79; PEX14; SERTAD2; HCFC2; TULP4; UBE2L3; ZNF175; ZNF44; ZBTB24; JUP; HOXD3; MED7; HOXC8; ATOH1; PRDM10; ZSCAN32; ZNF93; ZNF415; LYL1; BLZF1; EZH1; GFI1; TULP3; HOXC4; SRCAP; WWTR1; ZNF43; BCL11A; ZNF205; WNT4; PCGF3; ZNF671; HOXB2; SUZ12; DPF2; CEBPE; ZNF292; CDIP1; ZNF573; ZNF232; MYB; NLK; ZNF91; HOXC6; IRX5; ZNF215; CBFA2T3; FOXD1; TBL1XR1; ZNF248; ZNF468; CDK2; ZNF7; TXNIP; PRRX1; SOX13; TAF5; POU2F2; WWP1; NFATC3; BLM; HMGB3; INSR; ASCL1; DMTF1; PBX3; HOXB6; ZNF85; MED17; ZNF33B; CDK9; KLF10; TSC22D4; ERBB4; CCNH; HOXA11; DBP; CRYM; ID3; VDR; ZKSCAN7; RNF14; HOXA7; PRRX2; ARID5B; YAP1; CREB1; TRIM32; ZNF107; ZNF239; RREB1; MKL2; ING3; SPDEF; MXI1; CIZ1; DACH1; ZNF430; NR2F1; FOXA2; ZNF432; TERF1; ZMYND8; SMAD6; IRF4; NAB2; LEF1; SALL2; SHOX2; SPIB; FOXF1; MEF2A; TCF21; PAWR; HMGB2; RNF138; CREB3L2; CERS6; ZBED2; CUX2; TOX; MYBL1; ST18; NFYC; CALR; MYBL2; MECOM; MEIS2; NFATC4; MED1; ZSCAN18; IRF8; GATA2; TCF7L2; CITED2; FOS; ETS1; PSIP1; WT1; TRPS1; HOXB7
Down-regulation	154	RNF10; NFE2L2; FOXN2; AHR; MAFF; CREB5; ZNF423; HIPK1; CTNNB1; TGFB1; RUNX3; GABPB1; RORA; PTTG1; NR1D2; ZNF3; TFAM; GTF2I; CENPF; ARID5A; FOSB; TRIM29; MDM2; CHD1; TRIM16; UBTF; NCOR1; DEK; FOSL2; SETD2; HMBOX1; NAB1; XBP1; CEBPB; CCDC59; USP21; NFE2L1; KAT6A; AES; THAP11; CREG1; JUNB; TLE1; NKRF; EZH2; KLF3; ZNF512B; BBX; REL; VGLL4; ZNF281; MBD2; CNOT2; TLE4; HIF1A; MED13; EHMT2; HLX; CEBPA; ZEB2; CBFB; NR0B1; CEBPG; ACTL6A; NR1I3; TCEA2; ZBTB38; ASXL1; PQBP1; PNRC1; HEY1; TRRAP; ZMIZ1; HLTF; HIRA; BAZ1A; BAZ1B; RLF; CCNA2; REPIN1; HIPK3; ELF1; MAF; EGR3; KLF2; YWHAB; TP63; KLF4; TCF7; BHLHE41; ZNF133; NKX3-1; NFAT5; USP22; KLF6; PURA; CRY1; JARID2; MAFB; TRIM28; PBXIP1; RELA; AEBP1; ZFHX4; MYCBP; ZBTB18; BASP1; ZFPM2; GTF3A; TFDP2; DNAJC2; PIR; PTRF; SCAND1; BACH2; NCOR2; MTF2; ARID4B; RBL2; LMCD1; TRIP6; RBBP7; TAF10; DLX5; EGR2; NR1H2; ZNF148; IKBKAP; ZIC1; NRIP1; TBX2; SMAD3; PEG3; ETV5; TSC22D2; BCL3; MSX1; KDM5D; OSR2; FLNA; SOX4; IRF6; DRAP1; NFKBIA; MAGED1; RFX5; ETS2; TSC22D1; ID2; SPEN; ELK3; HES1; RELB; EMX2