Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62761	Le-135	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	TGFB1; HOXC10; TRIM29; SERTAD2; RARG; EZH1; RAD21; NFKB2; MMS19; INSM1; KLF5; GTF2I; ID1; PAWR; TULP3; CNOT3; NRF1; SMAD7; CREB1; PITX2; ZNF665; KDM5A; DACH1; BTAF1; MBD4; NOCT; RBPMS; BCLAF1; PNRC1; ZNF83; ZNF335; PPP1R13L; ARHGAP35; PEX14; MED14; TSC22D3; SUZ12; ST18; DLX4; ZNF224; TTF2; WHSC1; SMARCA1; ZNF131; OVOL1; WWTR1; CBFA2T3; GLI2; SSX1; PCGF3; MED20; CHD1; BCL11A; E2F8; MTA1; CREB3L2; EPAS1; PRDM14; FOXD1; MTDH; SOX9; TAF5; TULP4; SIX3; ZNF711; RBM39; HMBOX1; L3MBTL1; ZNF250; HSF1; SIRT2; SMARCD1; CARHSP1; ZMIZ1; GTF2IRD1; SOX15; PHIP; E2F5; PAXBP1; CCNT1; VGLL1; HIVEP1; HMGB3; RERE; BRIP1; VPS72; FOXJ3; NR1D2; HIRA; NR2F6; BTG1; ZNF304; PBX3; ASCL1; KLF10; POU2AF1; PIAS3; TRPS1; NCOA3; EN1; MYCN; SPIB; SOX13; TERF1; AGO2; CDYL; PAX5; NR4A2; MED17; HDAC5; SOX2; SSBP2; ETS1; NFATC3; FOS; RXRA; KDM5D; ZNF611; CLOCK; ASXL1; SNAI2; PAX6; ZNF211; ZMYND8; ZNF22; SMARCC2; MEF2A; CCNA2; KMT2A; PRRX1; FLNA; MYB; ZNF232; MTF2; ID3; RBBP7; SOX11; SMAD5; IRF8; ZNF217; SPDEF; DMTF1; ZSCAN18; STAT1; CDK2; ELF5; TP63; MEIS2; NANOG; ISL1; BIRC2; KLF4; ZNF586; FHL2; HDAC9; ID4; NKX3-1; TBX2; KLF9; EZH2; CDK7; RFX5
Down-regulation	132	ATF5; MYC; TLE1; CREB5; THAP10; ARID5A; PRDM12; MED7; ZNF226; KLF11; ECD; ELF1; PSMD9; SAP18; TFDP1; SP100; RORA; NEDD8; ETV5; CBX3; TCEB2; AR; GATA6; FOSL2; ZNF32; ZNF562; THAP1; ZNF654; ZBTB14; KAT6A; GTF3A; KAT6B; ADNP2; SMAD1; HMGA1; PIR; PTTG1; ZNF140; TCEA2; TP53; MITF; OVOL2; GCFC2; SOX17; BRD4; MKL1; SLC2A4RG; SUMO1; NFIB; HDAC1; NRIP1; RAN; EDF1; TAF7; THAP11; NR1H3; MNX1; CEBPZ; IFI16; C1QBP; EP300; C1D; MGA; SIAH2; SMARCA2; MAX; TXNIP; LPIN2; EN2; AIP; TGIF1; SHOX2; CCNE1; POU4F1; HSBP1; TADA3; SALL1; CREB3L1; E2F2; NFIX; MYRF; BAZ1A; NFE2L3; ZSCAN31; WWC1; HOXB5; EMX2; KLF2; BBX; TBPL1; TERF2; TCEA1; BATF3; RUVBL1; ZSCAN16; HDAC4; IKZF1; RNF138; HOXB7; ATF4; HOXB6; TAF10; NFYC; PBX1; PFDN5; PATZ1; GATA4; RNF6; IRF2; ARID5B; ELK3; ZNF268; ELF3; MYBL2; SUB1; ESR1; PCBD1; NR3C2; MXI1; MAZ; CUX1; ZKSCAN1; DRAP1; MSX1; LEF1; TRIM16; TRIP6; STAT5B; HTATIP2; HES1; SCAND1; BASP1