Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62731	Brompheniramine	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	HOXC10; MNAT1; ZNF589; NFX1; ONECUT2; DDIT3; UBE2B; TDP2; NCOA2; EZH1; NOCT; HOXA1; ZBTB11; ZBTB25; SERTAD2; RFX2; DBP; KLF13; KMT2D; HOXC4; NRBF2; SOX21; BARX2; JUP; MED7; MED12; SOX13; CIR1; HMBOX1; HOXC11; SIX1; KDM5C; POU2F2; TGFB1; SIRT2; NEUROD1; IKZF4; CEBPE; HOXC8; ZBTB32; DLX4; YEATS4; BATF; TLX1; HOXC13; LHX3; TFDP2; IRX5; INSM1; ZNF671; HCFC2; SMAD7; GFI1; TCF7L1; HMG20A; MKL1; SP140; LZTS1; RARG; PRDM5; SCMH1; NCOA1; ARID3B; SPIB; GATA3; HOXA3; PBX2; FOXJ3; ZHX2; MEF2D; TGS1; HMGB1; E2F5; PNRC1; MXI1; NFKBIB; ZNF10; NFIC; MECOM; RORA; SMARCD1; RAD21; ZNF43; VPS72; ZNF410; EP300; CREB1; IRF5; RFC1; SOX9; PIAS1; GLI1; ZNF217; CBFA2T3; SIM2; RNF6; TCF3; SNAI2; PCGF1; KLF10; PBXIP1; ZNF304; KDM2A; SFMBT1; STAT4; DMTF1; DACH1; CITED2; WWTR1; TXNIP; PAX6; MED15; SSBP3; RBPMS; ATF7IP; MYT1L; CHD7; ATF4; ID4; SMAD6; SOX11; SUZ12; ATN1; TERF1; MSX1; BARX1; RELB; TSC22D4; VDR; PRRX2; TCF21; IRF9; WWP1; CIZ1; FOXO3; CREM; BAZ2A; ZNF117; IKZF1; ZNF140; ZNF281; SSX1; ZNF586; SALL2; SMARCC2; POU2AF1; FOXC1; BACH1; EYA1; RXRA; TSC22D2; FOXG1; FOS; ZEB1; ARID5B; MEF2A; ID2; FOXF1; TWIST1; HDAC4; ZNF195; MEIS2; DLX5; ST18; ERBB4; STAT1; NR3C1; IRF8; MYBL1; LEF1; HES1; ERG; CDK7; TCEA2
Down-regulation	176	MBD2; SSRP1; CBFB; TFAP2C; KDM5A; TCEB2; RYBP; ZNF423; ERCC3; NAB1; DEK; CCNE1; TADA3; GTF2A2; EHF; MAFF; SAP18; YBX3; CEBPB; SETD2; ZBTB38; ZFP36L1; ECD; ZNF721; ELF5; GLI2; POU3F2; TOX3; SIX2; AHR; ZNF32; PEG3; TFCP2L1; MEIS1; EZH2; KAT2A; ZNF160; ZNF12; WWC1; ZNF672; TCF25; PBRM1; UBP1; ZFY; SPDEF; SND1; CBX3; CDC5L; NFIB; BAZ1A; SAP30; MED13; ZNF3; ZNF528; NCOA4; BRCA2; LITAF; FLNA; MAF; NFAT5; NKX3-1; NFE2L3; MITF; NRIP1; SRF; VGLL4; HLF; PTTG1; SATB2; POU4F2; FOXL2; FOSL1; BIRC2; HOXD1; DAXX; HOXD11; HDAC2; KAT8; DRAP1; ZNF146; NANOG; ETV5; NELFB; ZNF611; TLE4; C1QBP; KLF2; SMARCE1; JAK2; EN1; LOXL2; NR1H2; IRF3; RBBP4; CNOT1; RUVBL2; NFIL3; NPM1; SREBF1; KAT6B; SMAD4; PPARGC1A; ZNF652; SMARCA5; KAT6A; WDR77; BAZ1B; FOXA1; KLF4; TAL1; ARL2BP; YBX1; SMARCC1; USP22; GATA4; RNF138; MLXIP; TRIM28; GFI1B; PSIP1; TEAD4; SREBF2; RBFOX2; TRRAP; BRD4; PTRF; CALR; CCNA2; HSBP1; COPS2; ZNF264; ID3; NR4A1; NR4A2; SUPT4H1; LIN28A; SSBP2; TAF1D; TCEA1; SPEN; CREBL2; SCAND1; ZNF91; ELK4; JARID2; RBL2; TRIM16; ZBED2; NPAS2; PITX1; ZNF544; CEBPA; CERS6; MTF2; POU4F1; KLF6; ZMYM2; CBX6; KDM5D; MAFB; PLAGL1; RFX5; ZKSCAN1; ZFPM2; SATB1; PBX1; SUB1; NR2F1; TGIF1; ATF3; BRD2; HEY1; ELK3; STAT5B; NFKBIA; EMX2