Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62725	Mexiletine	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	CREG1; ARNTL2; CDC5L; HMGN3; ZEB2; ZFP36L1; MED20; TCF12; BMI1; BCLAF1; TGFB1; HOXC6; TBPL1; KLF10; AFF1; CREB3L1; XBP1; AHR; SNAI2; HLTF; HNRNPD; ID2; SMAD6; NRBF2; SMARCA2; SFPQ; MAGED1; SMARCA4; MED24; MED16; ZNF148; MNDA; TSC22D2; MDFI; NR2F2; ZNF468; PIAS3; TRIM32; ADNP; BCL10; DNAJC1; EWSR1; ZHX3; ZNF329; SUPT3H; YBX1; JARID2; CTR9; NUP62; KMT2A; TRIM22; CBFB; HDAC1; SALL1; KLF2; LEF1; APEX1; REPIN1; USP22; HMG20B; RHOA; RREB1; COPS2; PITX1; SIAH2; SSBP2; BIRC2; ASCL1; MYB; KAT6B; TLE4; CITED2; USF2; TRIM16; EYA1; TBL1XR1; FLNA; TOX3; IKBKAP; YWHAB; MEF2A; HES1; MEF2C; ZMYND8; ID1; ST18; PTRF; PSIP1; TFEC; NCOA4; HSBP1; ZBTB38; PLAGL1; MSX1; BRD2; MECOM; EZH2; CCNA2; TSC22D1; CDK7; EMX2
Down-regulation	60	CERS4; BCL11A; TWIST1; HOXC11; PLAG1; SERTAD2; TFAP2A; SHOX2; TGIF2; ZNF331; USP21; TCEA2; AEBP1; SMARCA1; HBP1; ZNF556; LHX3; HOXB2; MDM4; BNC2; POU4F1; TRIP6; MYBL2; CREM; RXRA; ZBED2; MKL2; ZNF432; MAFB; HIPK3; HOXB5; FOXN3; FUBP1; BATF3; DLX2; ZNF117; SALL2; IRF6; ID4; FOXC1; FOXO1; FOXF2; TCF7L1; ARID5B; BACH2; HOXB6; BASP1; HMGB2; TP63; KLF9; BTG1; EHF; ETS1; TBL1X; TBX2; ELK3; TRPS1; ZFPM2; PBX3; PEG3