Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62460	Ezetimibe	GSE92742	NPC	Human	24h	10uM	EID0350

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	ZNF331; TGFB1; CEBPD; NFATC4; ATF3; ZNF124; ZNF467; SPI1; KLF11; ZNF354A; LHX3; BNC1; ZKSCAN4; RARG; NFE2L3; ZNF665; VPS72; ZNF117; TCF7L2; TBX1; CERS4; HOXB1; ZNF195; HOXA5; TXNIP; TDP2; ZNF83; KLF13; LYL1; ZNF611; CDIP1; PHIP; ZNF415; ZNF701; ERBB4; MYBL1; CCNH; ADRB2; REL; MEIS1; HOXB2; AR; E2F8; ZNF721; SOX13; PRDM14; KLF3; MED15; CNOT3; ACTL6A; HBP1; LDB1; SPDEF; SRCAP; TTF2; ZNF544; TULP3; NFE2; ZNF394; TCEA1; CALCOCO1; ZNF33B; RORC; ZNF43; ZNF239; HDAC9; ARID5B; EVX1; ZNF85; POLR3C; ZNF44; PNRC1; TFAP2C; CBX4; SUMO1; IRF9; ELF4; STAT6; IRF6; BARX1; PBXIP1; OVOL2; NR1H2; NR4A2; PFDN5; HIC2; CBFA2T2; CNBP; ZNF273; VDR; PBX3; ZNF232; ZNF623; HSF1; WT1; AEBP1; VGLL1; NPAS2; BNC2; E2F3; TAF12; TRPS1; HOXD1; SMARCB1; FOXN3; JUP; TCF21; ZNF688; ZNF160; SREBF2; ZNF512B; ZFP36L2; ZNF589; ZNF91; ST18; BCL6; JUNB; MXI1; ZNF93; NFE2L2; TFAP2A; ZNF430; ATF5; GATA1; CBFA2T3; KLF9; ZNF652; PAWR; ETS2; EHF; ESR1; PSMC3; DDIT3; FOSB; FOXF2; AES; AHR; SOX17; ELF3; TFEC; TWIST1; IFI16; HIRA; ZNF580; CEBPB; MEIS2; ZNF131; PAX6; ZBED2; MNDA; NCOA2; GATA2; GATA6; TRIB3; TOB1; ZFP36L1; MITF; JUN; SSBP2; RBFOX2; NR0B1; ZMIZ1
Down-regulation	214	TAF9; TBP; SOX11; PTTG1; HMGA2; PARP1; FHL2; NRIP1; HMG20A; PUF60; CARM1; BRD8; USP22; PHF2; IKBKAP; TRRAP; HDAC2; HNRNPD; PHF8; SUV39H1; KLF12; BAZ1B; RBM14; DPF2; EP400; CITED1; SOX2; ATF1; ZBTB24; SMARCC1; RHOA; EZH2; CRK; AATF; PSIP1; RFX5; C1QBP; HMG20B; ZNF189; RBBP4; CCDC59; WHSC1; ECD; CREG1; SMARCE1; HSF2; ZNF410; SETD2; TCERG1; NFIL3; ING1; NUP62; PREB; NRF1; SSRP1; TBPL1; SMARCA5; FOXO3; SALL1; UBP1; ZNF292; MTA1; MLX; SMARCA4; TADA2A; ASCL1; RBPJ; CTNNB1; BATF3; ING3; ELK1; ZMIZ2; MAGED1; HEY1; ZEB2; RUVBL2; CBFB; NFYB; CNOT1; NFE2L1; BTF3; SMAD2; MTDH; MED23; SMAD4; TCF12; ZNF146; BMI1; NONO; BRD3; TRIM32; RBBP5; ORC2; HAND1; CREB5; FOXJ3; XBP1; ETV5; CTR9; PSMC3IP; BAZ1A; ZNF148; NEDD8; ZBTB11; TFDP1; TP53; TBL1XR1; BIRC2; TRIM16; ZKSCAN7; DDX54; YAF2; USF2; SIAH2; EDF1; RFX7; TBL1X; DNAJC1; MED24; EGR1; HCFC2; SNIP1; CENPF; KAT7; PSPC1; RNF4; NR2F2; BASP1; SMARCD3; MSX1; HMGB2; TRIM28; NFKBIA; POLR2A; NR1I2; ENO1; KDM5A; ZBTB38; CRY1; GTF2IRD1; RAN; CCNA2; REPIN1; EYA1; BAZ2B; ZNF226; RNF14; POU3F2; TRIP6; MED1; APEX1; SAP18; NCOR2; MYCBP; TOX3; BRD2; BCLAF1; PATZ1; ZNF24; VGLL4; PIAS2; SF1; PAXBP1; HEY2; GABPB1; TSC22D2; NCOA6; BATF; ASH2L; SIX1; HIVEP2; RNF10; CCNC; TAF10; SOX4; INSR; JARID2; TCF4; HDAC1; HDAC6; FOXG1; CHD7; PCGF2; SUB1; CHD1; NCOA4; CBX3; ZNF22; TAF1D; ZNF536; PITX2; HLTF; FOXO1; RBPMS; MNAT1; ZIC1; MYB; BBX; ING2; POU2AF1; ARID4B; LOXL2; HOXC6; POU4F1; NKX3-1; LMCD1; ERBB2; EGR3; HMGB3; ZBTB18; MEOX2; NR2F1; KLF2; KDM5D