Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62391	Pyrimethamine	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	64	SOX10; EMX2; TAL1; NR1H4; SCAND1; TAF12; CBX7; DNMT1; STAT3; ECD; MXD1; FLNA; TBL1XR1; NAB1; NFE2; CCNE1; NFATC1; PFDN5; ZFP36L2; IFI16; SSBP3; MTF2; NCOR2; REL; PEX2; HMGA1; ZNF217; CNOT6; HBP1; PNRC1; IRF6; HIPK3; TFAP2C; HTATIP2; RUNX3; RARA; RUNX1; YWHAB; ZKSCAN1; LITAF; MYRF; TSC22D2; ELF3; EYA1; BTG1; TFEC; ZNF266; HEY2; CDK7; SMAD1; YBX3; NFKB2; HOXD1; TRIP6; MECOM; SOX9; JUP; FOSL1; HOXC6; LEF1; HOXB2; KAT6A; TRIB3; CRK
Down-regulation	72	IKBKAP; SAP18; PBX3; HNRNPD; MEIS2; NKX2-1; RNF6; ZNF175; GATA6; NR1D2; BBX; RNF138; VEZF1; SNAPC4; FOXJ3; TCF21; RNF4; NR2F1; EGR2; BANP; DACH1; TOX3; ELF1; INSM1; GFI1; BCLAF1; SUZ12; PAX6; ZBTB38; DMTF1; CREB3L1; FOXF1; SMARCA1; HLF; SATB2; HAND1; MYB; ZNF423; IRF1; SIX1; PMS1; MAGED1; AFF1; ZBTB1; ZFPM2; BHLHE41; DDIT3; NKX2-2; RBL2; FOXE1; TEAD1; HMGB2; HOXB6; SALL1; MNAT1; CD3D; SMAD6; ISL1; OSR2; ST18; BMI1; ASCL1; HDAC9; ID4; SAP30; ZBTB20; EGR1; ELF5; ATF3; MSX1; PEG3; EGR3