Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62389	Tolbutamide	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	ABT1; EDF1; ZFP36L2; DLX2; BRD2; SCAND1; TAF12; FLNA; SMARCD2; ZNF264; BTG1; FOXO3; ECD; MAZ; SRCAP; PBXIP1; ZNF148; PMF1; BCL6; ZNF136; TADA3; CHD8; CARHSP1; PFDN5; MEIS1; FOXO1; ZBTB16; AR; RBBP7; MAFB; ING3; JUN; CDK7; MYRF; MNAT1; MXD4; MTF2; SALL1; CALR; ZBTB20; IRF8; WNT4; ZFP36L1; TCEB2; HIRA; KAT2B; NFAT5; MED1; YBX3; NFKB2; KLF9; KAT6A; ZNF266; CEBPB; HOXC6; MAF; WT1
Down-regulation	86	CREB1; ERG; BCL10; BRIP1; ZEB2; ZNF423; THAP11; ETS2; NUP62; TSG101; PPARGC1A; MNT; HOXD1; ZNF432; EED; MLLT10; XRCC6; ZNF606; SOX13; HLX; ZZZ3; WWTR1; TERF2; TLE1; RBPMS; CLOCK; CTBP2; NPAS2; NR2F1; ERBB4; RNF111; SOX15; IRF2; TGIF1; SMARCA5; MAFF; FOSL2; ZNF665; HMGB2; HMGA1; ZSCAN18; EGR2; SF1; MYB; SATB2; TRIM22; JUNB; NR3C2; HEY1; SFPQ; SHOX2; INSR; SUZ12; TRIM29; CRK; ST18; ZNF160; BMI1; USP22; TEAD1; TRIP6; HLTF; ID3; AFF1; EGR3; PBX1; ID4; TP63; TWIST1; NR4A1; PCGF2; ZHX2; BAZ1A; EGR1; FOSB; MYCL; BHLHE41; TOB1; BASP1; KLF2; ETV1; SMAD3; ATF3; NKX3-1; PEG3; FOSL1