Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62362	Anagrelide	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	RELB; HHEX; TSC22D3; SUPT6H; MED12; ID3; TFAP2A; VPS72; RAD21; TGFB1; DLX2; E2F5; SMAD7; PRDM14; HMBOX1; CREM; MBD1; NR2F6; MYBBP1A; ERG; ZNF273; MKL1; FOXJ1; TRPS1; FOXG1; HOXB1; PRDM12; CERS6; MEOX2; HDAC5; SIX3; ZNF423; SOX18; TP73; RARA; RRN3; ZNF232; NFE2L2; HOXD1; TERF2; RREB1; RXRG; AGO2; TP53; UBE2B; ENY2; SPI1; ZNF117; ZBTB16; SNAI2; HDAC4; THAP4; DLX5; TCF7L1; MNT; SUPT5H; ERF; HIPK1; PPP1R13L; CEBPG; PNRC1; PKNOX2; ZHX2; ZNF589; TRIM22; CREB3L2; TFAP2C; SUPT3H; TWIST1; FOXO1; SOX10; KDM5C; KLF7; ZNF512B; ID1; JUN; TEAD4; BCL3; RUNX3; PCGF1; CEBPD; CEBPB; CBX4; HBP1; TCF7L2; ZEB1; PDLIM1; IRF9; FOSL2; POU4F1; SMARCD3; MAFB; CDX1; PITX1; TCEA2; HMGB3; IFI16; NR0B1; HSF1; MKL2; MXI1; KLF3; FOXC1; TFDP2; REL; NRIP1; CNOT2; TXNIP; TCEA1; HOXD3; TLE2; STAT4; BTG1; BNC2; MYBL1; XBP1; SPIB; MYRF; AHR; TBX3; IRF6; CTNNB1; TRIB3; KLF13; MNDA; ZBED2; FOXF1; PEG3; LMCD1; CCNC; LEF1; TRIM29; INSM1; SOX9; POU2AF1; ESR1; CRK
Down-regulation	161	DRAP1; CITED1; EDF1; NFIL3; PBX3; E2F6; ZNF23; RBBP4; ETV6; NCOA6; SPEN; ZNF148; KAT5; SAP18; TBP; DACH1; ENO1; ZNF587; TCF20; SUV39H1; CCNA2; ZNF189; ELK1; SOX11; TCF15; E2F2; BRD2; ZBTB38; WHSC1; LPIN2; PSPC1; DMTF1; SALL1; TRIP4; ZBTB24; MED27; MED1; CDK8; DAXX; RBBP8; ZNF205; ZNF175; TEAD1; PHF2; ERCC3; JAK2; TFDP1; PCGF2; RFX7; PHF8; ZEB2; MED23; COPS2; LIMD1; TOX3; TBPL1; ZNF544; DDX17; PATZ1; ING3; BRD8; MTF2; ZNF83; HSF2; TCERG1; SMARCA2; SIRT7; UBP1; ZNF211; ZNF672; ZMYND8; ZBTB20; KMT2A; MED24; FOXO3; BCLAF1; ITGB3BP; DPF2; EMX2; PMS1; FOXJ3; CHD4; NR2F2; EGR2; RBL2; ZNF22; TSC22D1; NANOG; ZNF184; CHD7; IRF1; CBX3; NRBF2; DNAJC1; EP400; SCAND1; TADA3; MYB; ZBTB1; TSC22D2; ZMIZ1; ARID4A; POU5F1B; BMI1; MEF2A; RXRA; MNAT1; PURA; CTR9; RUNX1; NFAT5; KLF4; PKNOX1; BATF3; TAF1D; YBX1; SP3; HMGA2; ST18; HTATIP2; CEBPZ; KMT5A; ATF5; BLM; RBBP5; CDK7; RFX5; ID4; MAFF; RERE; RBPMS; BBX; HMGB1; ARID1A; KAT6A; TCF12; PTRF; ZNF551; TCEB2; ZMIZ2; TULP4; CITED2; CRYM; FOXN3; FOXD1; MEIS1; KDM5D; ZNF12; ZBTB18; JUND; DNMT3B; EGR1; EZH2; ELF5; FOSL1; WT1; SMARCD2; NFKB2; NR4A2; JUP; BASP1