Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62345	Podophyllotoxin	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	NFE2L2; MYC; CCNH; ARID5B; TCF7L2; PPP1R13L; MED15; RORC; LYL1; HHEX; PHF1; PAWR; HIPK1; LITAF; GATA2; TAF4B; UBE2B; PRDM14; NR1H2; TAF9; ERG; MYBL1; EN1; MXI1; TSHZ2; TFAP2C; BTF3; CEBPG; PCGF1; JUN; CBX4; ETS1; NR0B2; TFAP2A; FOXF2; TSC22D3; IRF6; ZNF215; ZKSCAN1; RBM39; CREM; NPAS2; FOXJ1; HBP1; ZNF331; VDR; RREB1; TEAD4; HOXC13; ZNF669; CALCOCO1; LHX3; ZNF354A; ZEB1; MBD1; CEBPA; PBX3; KLF3; CBX7; ESRRG; MITF; SRCAP; NFIB; EHF; BCL11A; CNBP; NFE2L3; KLF4; CAMTA2; SIRT7; TGFB1; ID3; RUNX1; ZNF264; CNOT3; TRIM29; ATF3; PSMC3; EPAS1; HOXD1; CSDE1; MAZ; ZFP36L2; DLX2; HDAC9; TCEA1; SATB2; SOX9; VGLL1; TAL1; VPS72; PCGF3; NFATC4; NR3C2; ZFHX3; FOXC1; NR4A3; PRDM2; DDIT3; TBX2; ERF; BHLHE41; NFATC1; HOXC10; ZNF430; CREB3L2; ZNF394; FOXI1; GATA6; KLF7; MAFG; ELF3; MED13; KLF9; PBXIP1; MAFF; PHF20; ATF4; HOXB6; ARL2BP; CDK7; ZNF665; JUND; HIRA; HLF; CEBPB; DNAJC2; ZNF124; RBFOX2; XBP1; MED6; CITED2; EMX2; HSF1; ZHX2; POU2AF1; TRPS1; REL; TSC22D2; GATAD2A; NR4A2; TOB1; ZFPM2; ZBED2; TBX3; TRIB3; JUP; YBX3; FOXF1; TULP3; ZNF652; NFKB2; CRK
Down-regulation	216	SOX11; NFIL3; PARP1; SOX2; BRCA1; SMARCC1; CCNA2; SUV39H1; HDAC6; PSIP1; TBP; NUP62; HMG20A; ZMYM2; TP53; EDF1; MED24; ZNF45; KAT5; IKBKAP; SOX4; ZNF432; MED4; TRRAP; ZNF76; DPF2; ZBTB1; ING1; HMGB3; ERBB2; PSMC3IP; ADNP; MED23; PHF2; MSC; ZNF133; MYCN; BACH1; ZNF516; SMARCE1; CBX3; BCLAF1; RBBP7; RBM14; WDHD1; SALL1; IRF4; ZNF606; ZNF292; BMI1; ATF1; TADA2A; KDM2A; ZNF148; ZFP64; FOXJ3; EN2; SUZ12; PRKDC; TBL1XR1; TCF12; TGS1; CBX5; CARM1; PLAGL2; ZKSCAN7; POU2F1; PHF8; MAGED1; NCOA6; HDAC2; ZNF226; SETD2; DDX5; NONO; MYCBP; ZBED1; ZNF248; TRIM32; ZNF587; ISL1; ZNF189; MED7; RNF6; TRIM22; ZNF282; ETS2; PCGF2; MED1; TFDP1; E2F6; TAF7; ZNF410; HMG20B; MSX1; BRD8; HSF2; BCOR; ZNF136; ING2; URI1; RBBP4; CHD7; EGR2; MNAT1; TRIM28; SMARCA5; RERE; UBP1; ZNF329; ZEB2; GLI2; SUB1; KAT7; SIAH2; DNAJC1; TADA3; ITGB3BP; ETV1; BATF3; UBTF; ZNF146; HMGB2; NRBF2; RNF141; ZNF443; EZH2; PKNOX1; NELFB; SMARCC2; HMGN3; TAF11; KDM5D; ZNF184; C1D; VGLL4; TAF1D; RLF; ZNF672; RHOA; ZNF177; RFX5; REST; ELF2; ARID4B; BATF; EP400; LZTS1; JARID2; IL16; IRX5; DNMT3B; HDAC1; IRF2; SP3; SIX1; ZNF84; CRY1; AATF; POLR2A; STAT1; SIX2; PTTG1; CHD8; PEX2; ZNF532; CBFB; RFX7; CTR9; ZNF302; ZNF267; CREB3L1; SLC2A4RG; NKX2-2; HLTF; TFDP2; SMARCD3; BLM; LMCD1; DDX17; TEAD1; FOXM1; ATF5; PLAGL1; ZNF22; CENPF; PAX5; SMAD6; EGR3; SAP30; TCERG1; YWHAB; PIR; CEBPZ; MAFB; AEBP1; BAZ2B; EYA2; ZBTB38; NR1H3; SMARCA2; EGR1; POU4F1; SMARCA4; TCEA2; TWIST1; ZBTB18; RBPMS; CRYM; C1QBP; PUF60; LEF1; ID4; ASCL1; NR4A1; SMARCD2