Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62329	Protriptyline	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	FOS; RFXANK; DRAP1; ZNF516; HOXC6; FOXL2; SCAND1; UBE2I; ZNF263; HSF2; PHOX2B; HDAC5; MDM4; ZNF711; ZNF410; BRF2; SETD3; SIAH2; EP300; TCEB2; HMGB3; FOXO3; HMBOX1; TRIM16; RAN; MSX1; TBL1XR1; LPIN2; NFATC1; NCOA6; KMT2A; ERG; ECD; ATF6; RBBP4; TCF7L1; JUNB; PBX2; PURA; HIVEP2; BRD8; PSPC1; JAK2; EP400; NEDD8; RCOR1; ZSCAN31; ZNF24; ZNF764; HDAC1; REPIN1; TCF7L2; BIRC2; JUN; MYB; MEOX1; PHIP; ZEB2; TBPL1; E2F5; CTNNB1; CREBZF; HIPK3; SMARCD3; KLF6; PCGF2; CDK7; ID1; PGR; MAFG; SIM2; DDX17; TSC22D2; SATB2; BAZ2B; CEBPB; ATF4; RBBP5; NFE2; FOSB; EMX2; HEY1; MBD2; JUND; ZNF721; ELF3; CITED2; FOXD1; PITX1; YWHAB; LMCD1; TCF12; KAT6A; NR2F2; TBX3; MNDA; NR4A1; ZNF652; ASCL1; POU2AF1; EZH2; PEG3; ATF3; EGR1; CRK
Down-regulation	86	ARNT2; GMNN; TFAP2A; TDP2; ZBTB38; SOX13; RNF6; MYBL1; ELF4; VDR; ETS1; BBX; CREB1; TEAD4; TGFB1; THAP10; NUP62; NFIB; PAX6; NR1I2; NANOG; WWTR1; ZNF232; HOXD1; CEBPD; FOSL2; EPAS1; GATA6; PMS1; TLE1; RORA; HOXB13; HDAC9; KAT2B; NR1D2; SMARCA2; FOXC1; TERF1; CTBP1; RYBP; CBX3; PAWR; FOXF2; ZNF148; POU5F1B; DMTF1; SNAI2; TFCP2L1; IFI16; KLF13; USP22; ZNF443; TRIM22; SOX10; FOXF1; ZBED2; NPAS2; ERBB4; SMAD1; AHR; DEK; ZNF331; ZBTB18; ZNF266; HMGB2; BHLHE41; EHF; MEIS2; CRYM; NFATC4; WT1; MAFB; PBX1; BNC2; NFIC; BRD4; BMI1; TULP3; HOXB6; HOXA5; ETV1; NFKB2; KDM5D; LOXL2; FOSL1; BASP1