Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62311	Guanfacine	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	59	PPARG; FOXA1; SOX10; HMBOX1; PIR; SIX2; NRIP1; SIM2; PURA; CUX1; CTNNB1; COPS2; ZMYND11; PHF8; STAT6; REPIN1; MITF; BATF; ZBTB16; TBL1XR1; HEY1; ARID4B; SMARCA1; AFF1; TRIP6; STAT4; TRIM22; MSX1; NR2F2; ZKSCAN1; ATF4; RUNX3; HTATIP2; POU4F1; NKX2-2; FOXC1; MED6; NCOA3; YWHAB; SIAH2; IRF7; CREM; MYRF; ID1; SAP30; ELK3; ERBB4; HOXC6; USP22; TSC22D2; TRPS1; TCEA2; MECOM; EGR1; KAT6A; TOX3; CRK; EGR3; SMARCA4
Down-regulation	51	ATF1; MEIS1; YBX3; NANOG; CITED1; PBX3; MEIS2; ZIC3; SP140L; NFE2; EMX2; PBX1; KLF4; TFAP2C; HOXB6; HAND1; TCF4; ZNF264; SUZ12; TOX; DACH1; YBX1; WT1; HDAC9; ZBTB20; BHLHE41; CREBL2; GATA6; PAX5; ZFPM2; BCL11A; CBFA2T3; TCF7; HOXB5; ISL1; RORA; LIN28A; ZNF721; KAT2B; FOXF1; CEBPZ; TWIST1; TFEC; MAF; LOXL2; POU2AF1; FOSL1; PEG3; NFKB2; NR4A2; HOXB2