Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62245	Mexiletine	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	PPARD; EED; SMAD7; HOXC10; TCF4; TEAD3; ZNF444; PPP1R13L; CEBPA; PLAGL1; HIC2; MNAT1; TCF3; BARX1; NPM1; ZNF512B; HOXA11; TGFB1; ZNF354A; ELK3; TLE2; ETS2; CCNH; PLAG1; MED12; TFAP2C; IRX5; ZEB1; TRIM22; ZNF556; BCL3; TCEA1; IRF8; ZMYND11; RUNX3; ZNF195; TRIP6; HDGF; SPI1; ZNF117; ATN1; CCNE1; CNOT6; PITX1; TGFB1I1; KLF7; CHD7; CTBP2; CEBPG; MED6; CNOT2; TRIM29; WNT4; ZNF580; PURA; E2F8; ELF3; MBD2; XBP1; ZNF430; ZNF22; IRF2; EMX2; IL16; TP63; ZNF91; ZNF665; NFE2; RUNX1; KLF5; POU4F1; GTF2IRD1; GRHL2; TOX; EYA2; CEBPB; KLF6; PAX5; SMAD1; BASP1; ID3; BHLHE41; TRIM16; SHOX2; IFI16; ZBED2; TRPS1; TWIST1; TCEA2; POU2AF1; KAT6A; JUP; TRIB3; CRK
Down-regulation	78	HMG20B; SOX11; UBE3A; HDAC4; TRIM24; CERS6; USP22; ZNF672; ZFPM2; HHEX; DMTF1; TCF21; MED1; ING1; NFE2L3; KAT7; ATF7IP; WWTR1; DLX2; EGR2; MAFB; PROX1; EGR3; EP400; LMCD1; PIAS1; SMAD2; MYRF; INSM1; FLI1; COPS2; EGR4; MLX; CRY1; ZNF423; NFAT5; CAMTA1; HIPK3; PNRC1; TSC22D1; BRD2; PBX1; AEBP1; MEIS1; CDC5L; ZBTB1; ZNF24; NR4A3; PIR; TOX3; SNIP1; BBX; TOB1; CARHSP1; TSC22D2; NFIB; KAT6B; SIAH2; ZMIZ1; TOPORS; ZBTB18; KLF9; TAF10; KLF10; CDK7; ST18; RBPMS; ZNF331; PCGF2; CEBPZ; CRYM; EGR1; NR4A2; WT1; FOSL1; NFKB2; ATF3; NFKBIB