Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62231	Donepezil	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	SUV39H1; KLF4; GATA2; SP1; HLF; KDM2A; BHLHE40; PBX3; RBM14; SIX3; SOX13; GTF2I; ZEB2; BCL11A; ZMYND11; ETS2; TRIM22; HLX; HIPK3; FOSL2; KAT8; FHL5; BPTF; ASH2L; NCOA4; TRIM25; NPM1; EYA1; NFKBIB; HIVEP2; YAP1; ENO1; AES; BCLAF1; MKL2; TEAD4; RARA; CALCOCO1; EPAS1; BCOR; ETV5; DACH1; NELFB; RERE; CREB3L1; STAT6; TCF21; ZIC1; PITX2; MED24; SMARCA2; SMARCD2; MEOX1; RARB; MED6; PPARGC1A; HOXC6; GATA6; TOX3; USF2; YWHAB; CRYM; MEOX2; HOXC10; KDM5D; FOXF1; E2F5; EMX2; FOXG1; ZNF665; PTRF; PIR; FOXD1; MYB; MECOM; NKX3-1; IFI16; ZKSCAN1; HOXB2; SIX1; BAZ1A; SMAD4; SMAD6; NCOA1; VDR; ZNF652; YBX3; TRIM29; RBPMS; BASP1; FOSL1; ZSCAN18; KLF9; NFKB2; BMI1; INSM1; TFEC; LEF1; CRK; KAT6A; PEG3
Down-regulation	92	RUVBL1; HHEX; TSC22D4; ZNF562; KDM4C; TRIP4; ZNF354A; RBBP8; ZNF3; TDP2; CITED1; ETS1; ZNF532; ZNF133; FUBP1; PMS1; ZNF175; ZNF410; SAFB2; TOX4; GATA1; DMTF1; HOXA1; CDK9; E2F3; BNC2; ZNF211; PAXBP1; MTDH; SND1; TFDP2; CHD8; KLF6; CUX1; SALL2; MYBL1; JUN; MYRF; NFE2L1; HMBOX1; TERF2; SLC2A4RG; BLZF1; CD3D; NCOA3; URI1; KLF13; TRIB3; ZNF281; ARL2BP; MAF; HTATIP2; EYA2; KLF11; MXI1; CTBP2; GRHL2; ZMIZ1; ZNF593; ATF5; NFIB; KLF7; CREB5; ZNF12; STAT4; ZNF83; ARID1A; TBX3; CHD4; HIRA; TP63; ATF3; DNAJC1; ZFPM2; ST18; TOB1; ID3; AEBP1; KLF2; PBX1; ZBTB20; EGR1; LOXL2; CEBPB; EGR3; TULP3; TCEA2; TWIST1; NFAT5; ID1; BHLHE41; WT1