Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62217	Picrotoxin	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	WWTR1; MITF; ZNF134; SP100; REST; NSD1; ZNF552; ZIC1; CEBPA; DNMT1; MYBL2; ZBTB11; PLAGL2; RFXANK; NPM1; CHD3; CCDC59; FEV; TGS1; NCOA4; ZNF468; POLR2A; ECD; ALX1; NKX2-2; MAML1; BCL11B; TRIM22; BAZ1B; DNAJC2; IL16; HTATIP2; PLAGL1; NCOR2; ETV5; ELK1; MEOX2; STAT3; FLNA; ASH2L; RUNX3; BLM; RBM14; ZFX; STAT6; TRIM28; POU5F1B; SFPQ; SLC2A4RG; MED6; ZNF532; BRPF1; TLE2; CTR9; MYCN; TGFB1; BATF; NKX3-1; CD3D; GLI2; PITX1; HIC2; IFI16; TRIP6; ZNF394; ZNF430; ZNF467; BRD4; TCEB2; PHIP; IRF8; ZKSCAN1; CDK7; TADA3; DNMT3B; RBPMS; YWHAB; PIR; JARID2; PBX1; ZMIZ1; REL; MEIS1; BASP1; BTG1; PEG3; MAFB; KAT6A; IRF7; TCEA2; TBX3; MECOM; TFEC; KDM5A; EGR2; CRK; HOXB2; ASCL1
Down-regulation	86	CHD7; HMG20B; GATA6; PBX3; TERF2; CITED1; MEIS2; PCGF3; RAD21; ZNF562; KDM4C; E2F3; PAWR; TCF7L2; SP2; ZNF3; TCF3; ZNF423; ZSCAN9; THAP11; ILF2; ZNF91; FOSL2; ZNF573; CTBP2; IRX5; ID3; ZNF22; ENY2; FUBP1; DACH1; RFX5; VPS72; MYT1L; ZFP36L1; URI1; E2F5; TOX; BACH2; INSM1; CHD4; ZBTB18; YBX1; ETS2; ERG; MYB; ZNF217; KLF11; ZNF721; AEBP1; KLF2; TRIM29; SUZ12; ZEB2; ZHX2; NR4A2; TBL1X; MNAT1; ZNF160; HMGB1; NKX2-1; INSR; TAF1D; GTF2IRD1; STAT4; ID1; PIAS1; MLXIP; APEX1; LOXL2; MAFF; ATF3; MYBL1; TWIST1; YBX3; MXI1; ZNF331; TOX3; EGR1; EGR3; PCGF2; NR4A1; NFKB2; FOSL1; WT1; BHLHE41