Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62185	Racecadotril	GSE92742	NPC	Human	24h	10uM	EID0349

Response Information :

Types	Number	Response transcription factors
Up-regulation	298	NR3C1; GATA3; IKZF1; NFE2L2; PPARD; HTATIP2; BACH1; ADRB2; DR1; MTA1; ARID4B; GATA6; BCL10; HOXC6; WWP1; BAZ2A; RELB; MAFB; MTF2; HLX; BTG1; PML; ZNF586; ERCC2; CREB1; FOXO1; BCL3; CEBPD; TCF4; MED7; ZNF226; GATA2; BRWD1; ZBTB43; NRBF2; EHMT1; SERTAD2; ZBTB17; ZNF165; ZEB2; CDK9; SKI; CNOT3; ZBTB48; SIRT7; NPAT; ASXL1; BACH2; BHLHE40; ZNF215; BCOR; GFI1; HOXC5; MKL1; ETS2; ZNF131; POU2F2; MEF2A; NR1D2; NFE2L3; LMX1B; HOXC4; ZNF7; ZNF236; BBX; PREB; ZNF107; ZNF45; TAF7; ATF7IP; MNAT1; ZNF34; NR3C2; ZNF180; ZBTB14; ANKRD1; PRMT2; ZNF335; FOXH1; NFATC1; GCFC2; POLR3F; YAP1; MXD4; MED21; ZSCAN16; ZNF354A; ARID4A; KMT2B; SP1; TFEB; ZNF274; NELFB; ZBTB39; NR0B1; MBD2; GATA4; SNAI1; MAK; ZFX; SSX1; EPAS1; TRIP11; HDAC4; UBTF; HOXA6; NUP62; ZNF276; FOXN3; SP2; REST; PIAS3; ZNF211; GON4L; PNRC1; KLF13; CIC; NR5A2; ZNF467; MYRF; KDM4C; FOXI1; MYBL1; ZNF227; HSF1; MAX; MITF; BLZF1; HOXC10; PTRF; ZNF267; LMCD1; SP140; MDM4; ZBTB38; ZSCAN31; E2F1; SMAD7; FOSL2; C1D; CTBP1; HIVEP1; TCFL5; CDK8; HOXD3; NFYA; ZNF688; THAP1; TCF3; FLNA; RUVBL2; ZNF770; FOS; NSD1; MECOM; SKIL; AGO2; VDR; PGR; MED6; ZNF556; ZBED4; DBP; OVOL2; CHD7; ZNF134; RNF141; RCOR1; VEZF1; TAF9B; PAWR; TGIF1; ZNF771; PAX5; TRIM32; IRX5; SIAH2; SUPT3H; IRF2; ARID3A; UIMC1; JARID2; SMAD1; EGR2; NR2C2; TOPORS; ZNF426; NR1H2; FOXL2; TSC22D2; GABPA; LHX6; RNF14; IL16; TXNIP; ENO1; PLAG1; E2F5; RFX5; CITED2; ATF5; IRF1; TRPS1; PIAS2; ZSCAN9; TRIM33; JAK2; ZNF177; CTBP2; TFDP2; SPI1; KLF11; CHD1; ZNF281; MZF1; HIPK2; MSC; HMGA1; SOX17; RBL2; HOXD10; SOX18; PIR; HOXA1; TGFB1; SFMBT1; POU4F1; BCL11B; PPARGC1A; ZNF136; HMGB2; NFKBIB; EBF2; ZNF189; RFX7; CBX6; ZNF430; HLF; SMAD3; KDM5A; ELF5; YAF2; CREBZF; EGR4; LOXL2; WNT4; MYT1L; CREG1; ETV1; EMX2; ELF3; TFEC; CREB5; HEY2; XBP1; SPIB; OSR2; SIM2; ZBTB18; SALL1; AEBP1; KLF4; JUNB; RARA; TFCP2L1; SIX1; ESR1; TFAP2C; NCOA3; PIAS1; NR4A2; ZKSCAN1; TCERG1; SLC2A4RG; TAF10; ZNF12; TRIM16; ZNF652; TERF1; NFAT5; ID3; KLF9; BASP1; SNAI2; ZNF266; AHR; CEBPZ; WT1; KLF2; EGR3; JUP; NR2F2; MNDA; NFKB2; TBX3; FOSL1; EGR1; CRK
Down-regulation	284	SOX2; HMG20B; NONO; IKBKAP; DRAP1; TRIM24; SPDEF; CITED1; ZNF589; TLE4; HEY1; RAD21; ZNF432; SSRP1; ETV5; SAP130; SRF; ZFHX4; FOXF2; NR2E1; GABPB1; PFDN5; ZNF219; SALL2; BTF3; TOX4; RFXANK; HCFC1; SAP18; CTCF; PBX1; PBX3; GTF3A; SUB1; MDFI; NCOA6; SND1; HMGB3; RXRG; EN1; NPM1; TOX; TEAD4; BAZ1B; MAGED1; PQBP1; CDYL; ZNF587; ZIC1; ATN1; AES; RBM39; WIZ; ECD; NPAS2; TCF12; POLR2A; HMGB1; ETV4; PCBD1; SSBP2; ILF2; PBRM1; HDAC2; PMF1; SREBF2; PAX6; BCLAF1; ETV7; HMGN3; ZNF91; BRD7; SUV39H1; SAFB; DNMT1; RREB1; FOXA1; CALR; GATAD2A; PRDM10; SATB1; SP110; PHF1; ZNF175; MLX; ZNF232; PSMC3IP; HDAC6; TFAP2A; E2F6; TAF6; SMARCA1; ZNF93; PHF20; UBE3A; TGFB1I1; SMARCA5; JUND; ZNF117; SAFB2; ZNF544; MNT; KDM5D; CCNC; URI1; RNF138; ZNF43; POU3F2; APEX1; SMARCE1; PLAGL1; GFI1B; INSR; LHX2; TSC22D3; PRDM14; RYBP; TRIP6; COPS2; DACH1; FOXM1; PHIP; GTF2F1; DNAJC2; UBE2I; GTF2IRD1; PSIP1; ZNF3; CRYM; RFC1; ZNF654; FOXF1; HOXB3; FOXJ2; CREM; ZNF768; TBX19; ZNF141; KAT2A; PAXBP1; ZMIZ1; CCNA2; PMS1; MKL2; VGLL1; ZNF32; ST18; RLF; ARL2BP; NEDD8; ZNF337; BMI1; AIP; ZNF606; ZNF24; SOX13; ZNF22; RBBP4; HNRNPD; SUPT5H; CDX1; SF1; JUN; CBFA2T2; ZNF500; EDF1; MED12; CHD8; CNOT1; IRF9; ZBED1; SETD2; TRIM22; NRIP1; ZNF74; RXRA; ATF6; NHLH2; ZNF669; ZNF593; BCL11A; TCEB2; ZFP36L2; MYCN; PSMC3; CBX3; RELA; TP53; MYC; ZFP36L1; VPS72; RAN; TDP2; SMARCD3; SIX2; PRKDC; MLXIP; NKX3-2; CDK2; HOXD1; ZFP64; SAP30; DAXX; UBP1; ZNF711; DPF2; NFKBIA; LIN28A; EP400; ARID1A; ERBB2; PITX1; RNF6; ATF4; LHX3; CHD9; CREBL2; E2F8; INSM1; TULP3; PCGF2; BRD4; RBBP7; DDX17; KLF5; PA2G4; CUX2; NFIC; SCAND1; NR4A3; ZFHX3; PRPF6; ASCL1; HOXB5; HOXB6; MAFF; CDK7; TRIB3; HIRA; ZNF83; BRD2; ZNF611; SOX9; NKX2-1; ZFPM2; MED24; SMARCA2; ZBTB16; NR2F1; HDAC9; TBL1XR1; ABL1; CEBPB; ZNF302; USP21; DNMT3B; TCEA1; MAF; TAF1D; CD3D; MED13; ZSCAN18; MYBL2; TCF7; HES1; NFATC4; FOXG1; ZNF331; BHLHE41; GRHL2; ZNF160; KLF6; SUZ12; CENPF; ID4; ATF3; MYB; HOXB2; ZBED2; MED1; MEIS1; SMARCD2; ID1; TCEA2