Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62157	Pirenzepine	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	XBP1; BRIP1; EHF; NFYB; ZIC1; HMGA1; ILF2; TFAM; E2F5; DEK; ARID4A; THAP1; ZNF443; ZNF107; PBRM1; USF2; ZMYND11; PSIP1; MYCBP; DNAJC2; ZNF226; ZNF23; GMNN; KLF2; PAWR; MDM2; HMGA2; BMI1; USP22; MEF2A; DNMT3B; ZBTB11; NRBF2; GTF2I; NR1H3; ZNF468; MED6; LEF1; VEZF1; UBE2B; SMARCA2; CBFB; ING3; TSC22D4; BCL10; CEBPB; NR1D2; TOPORS; STAT1; PRKDC; RBBP8; MAGED1; YAF2; GABPA; ITGB3BP; TOX; UBP1; SOX9; BHLHE41; TSC22D1; TERF2; ZBTB38; CHD1; NPAS2; ZKSCAN1; POU4F1; HLF; CEBPG; NLK; TSC22D2; BCL6; ZBTB18; MDFI; HIPK3; ATF1; BIRC2; SMAD4; TRIP6; NPM1; CRY1; HMGB1; NFKB1; NFIB; MYB; BAZ1B; HOXA5; TRPS1; BBX; SMAD1; STAT6; SIX2; TRIM22; FOXC1; MYBL1; CDK7; NUP62; TGFB1; CALR; ZNF131; ZMYM2; BASP1; ZNF12; CRK; ID3; MTF2; SPDEF; DMTF1; NFATC3; EED
Down-regulation	75	TCF21; AIP; MAFB; HLX; NR0B1; AATF; NFE2; HOXB5; IL16; TRIM24; NFATC1; CERS4; ALX1; NCOA2; ZNF133; DDX17; OSR2; PRDM1; ZEB1; EP300; NCOA6; MKL1; KAT2B; INSR; TFAP2A; DACH1; IRF6; IRF4; LHX3; AEBP1; ELF3; HOXB6; ZNF516; PSMC3; PIR; TCEB2; ZNF532; RBPJ; KLF11; ST18; GFI1; NKX2-1; FOXF2; BCL11A; FOXO1; GRHL2; HOXD3; ZMYND8; WNT4; ZNF589; PFDN5; TCF7L1; ZNF467; STAT4; ESR1; TBL1X; MAF; GATA6; WT1; BNC2; PHIP; EYA1; CREB3L2; TFDP2; ID4; TRIB3; SOX17; ID1; KDM5D; MXI1; FOSB; TCEA2; PEG3; SMAD3; EGR1