Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62155	Pyrimethamine	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	XBP1; ZNF652; SERTAD2; ORC2; SFMBT1; PCGF2; GATAD2A; TRIM16; ELF2; TRIM28; MAGED1; MED1; BRD3; PBRM1; MED6; MGA; LITAF; CTBP2; CHD7; ZNF430; TCF12; ZNF551; ZKSCAN1; MAZ; ASCL1; E2F2; VEZF1; SIX1; SFPQ; AES; DNAJC1; BRCA1; USF2; KAT7; CTR9; ELK3; JARID2; ZNF587; RBBP5; REPIN1; ZEB2; ZBTB18; KDM2A; CLOCK; TSC22D2; NKX3-1; ZNF148; ERBB2; SMARCA4; PBX3; SOX4; NR1D2; FLNA; LEF1; KMT2A; ZNF44; ZBTB11; FOXO3; MED13; IRX5; HOXC6; PIAS3; EDF1; TCF4; MTF2; CRY1; MNAT1; ZNF91; DNMT3B; GTF2I; MYB; MAX; ZMYM2; BIRC2; HLTF; SIAH2; AFF1; SOX9; CHD1; NUP62; SAP30; IKBKAP; NR2F2; HDAC6; CRK; TLE1; C1QBP; CERS6; HHEX
Down-regulation	47	EN1; CEBPD; KLF10; VDR; ERBB4; NR1H2; ZNF83; TOX; IRF6; EYA2; SOX13; DDX17; BACH2; FOXG1; DLX5; KLF4; ZEB1; KLF11; EP300; SOX17; CEBPB; SPIB; STAT4; FOXF2; CCNH; IFI16; TRPS1; ENY2; HLF; EMX2; MYBL1; NANOG; CREM; HEY1; MEIS2; SOHLH2; FOS; MAF; MAFF; ATF3; PEG3; HOXD1; EGR3; NFATC3; BASP1; EGR1; TCEA2