Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62138	Nizatidine	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	129	CEBPA; KDM5A; ING1; XBP1; IRX5; KLF2; BRD8; PAX5; DYRK1B; ZNF282; SFMBT1; ARNTL; FOS; BRD3; DDX5; USF2; BRCA1; PURA; ETV5; SERTAD2; SIX1; E2F5; ATF6B; SOX15; SETD2; NR1D2; CITED1; BCLAF1; PCGF2; TLE2; SMARCC1; TCF4; CTNNB1; UBE2I; HDAC1; ZBED1; DDX54; CTBP2; BANP; TBX3; SMAD6; TBL1X; BHLHE41; TOB1; CREB3L2; GTF2IRD1; SMAD2; SCAND1; PHF8; SATB2; HAND1; CEBPB; SUV39H1; BRPF1; CHD7; PIAS3; MTF1; EDF1; TFAP2C; ERBB2; ZNF302; MNAT1; FOXO3; POU3F2; MLLT10; SOX4; RBM14; WNT4; TBL1XR1; FOXC1; BCL6; KLF7; FOXJ3; MYCBP; NFIB; KLF12; MED6; HTATIP2; DNAJC1; TSC22D1; NKX3-1; MDFI; ING3; RREB1; MXD4; GATAD2A; SMARCA4; PSMC3IP; HOXC6; PTRF; DNMT3B; ATF4; SAP18; SOX9; TGIF2; PBX3; SIM2; MXI1; LOXL2; HLTF; DLX2; NFATC3; SIX2; BBX; URI1; MAGED1; PATZ1; ASCL1; ING2; ZBTB38; TRIP6; MSX1; YWHAB; LEF1; SMAD3; FOXD1; RBPJ; SMAD1; DEAF1; VGLL4; CHD1; NUP62; RBPMS; CDK7; CRK; TLE1; HMG20B; BASP1; TCEA2
Down-regulation	119	GTF2A2; SUZ12; TCERG1; ZMIZ1; ZSCAN9; PTTG1; CENPF; ZNF331; CEBPD; HOXB2; PNRC1; HOXB5; HMGB2; KAT2B; KLF11; ZEB1; TRIB3; HLX; ACTL6A; ZNF117; NR1H2; ZNF224; NOC2L; SP140L; ZKSCAN4; IRF1; TCF21; TGFB1; MED14; HDAC9; BACH1; RBFOX2; ZBTB20; ZNF529; ZNF136; ZNF232; C1D; MLXIP; JUN; NFE2; BCOR; PAXBP1; RING1; PGR; PBXIP1; KLF10; IRF6; PEG3; SOX13; AHR; CUX2; GMNN; SSX1; HOXA4; PSMC3; ZNF83; TRPS1; MNDA; EP300; USP21; CD3D; NCOA3; PLAGL1; ST18; TFAP2A; NFE2L2; FOXN3; HOXD11; DLX5; SALL2; RORA; TOX; WT1; RYBP; MYRF; ZNF91; PFDN5; JUP; SOHLH2; IFI16; CCNH; PBX1; ZNF135; ZNF85; FOXG1; OSR2; RAD21; ARID5B; ZNF667; ZNF264; BCL11B; DDIT3; YBX1; HDAC4; ZNF124; VPS72; ENY2; ZNF165; HLF; ZBED2; ZNF623; RNF6; HOXA5; NANOG; WWP1; AEBP1; NFATC4; ZFPM2; HIC2; SSBP2; ZSCAN18; TBX2; TOX3; IKBKAP; HOXD1; HHEX; ETS1; GATA6; EGR1