Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62094	Protriptyline	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	42	MXD1; KDM5A; HTATIP2; ASCL1; BRD3; GATAD2A; TBL1X; KLF2; CREB3L1; DNAJC1; MAGED1; USF2; RXRA; MED13; PCGF2; ZNF711; TRIM16; SOX9; TCEB2; IRX5; ZBED2; AR; EDF1; SUB1; PITX2; DNMT3B; ZNF148; ZBTB18; BCL11B; MDFI; TCF4; SREBF1; HMGB3; ATF5; HLTF; SIX2; CTBP1; CHD1; HMGB1; MXI1; CRK; KDM5D
Down-regulation	61	CDK2; GMNN; PAX5; MITF; MED15; ERBB4; TULP3; NPAT; PNRC1; HDAC9; PCGF1; SMARCB1; MBD2; MEIS2; SOX17; PHF20; EP300; EYA2; HOXB6; TOX; PSMC3; HEY1; ZNF580; HMG20B; KLF10; FOXM1; TRIM29; EMX2; KLF9; CREBZF; CCNH; WT1; ZNF623; HOXB2; SOX10; ZNF512B; CCNC; ID1; ZMYND8; MECOM; MEIS1; TGFB1; PIR; CREBL2; TP63; CITED2; MYBL1; HEY2; HOXA5; ID3; EGR2; NR4A1; HOXD1; ATF3; EED; PEG3; SMAD3; TCEA2; EGR3; NFATC3; EGR1