Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62074	Aliskiren	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	104	ORC2; PITX1; BRD3; BRD8; TEAD1; ASH2L; MED1; PBRM1; POU3F2; POLR2A; FOXD1; MAGED1; MSX1; PCGF2; TBL1X; RCOR1; TCEB2; USF2; EDF1; SNIP1; MTA1; MYCBP; ZNF516; SERTAD2; PKNOX1; CHD7; IRX5; PIR; SOX9; ASCL1; RFX5; PURA; EP400; TOB1; TAF10; SETD3; KLF2; ZNF587; NFAT5; BRPF1; DNMT3B; CNOT1; ING3; TCF12; BRD2; SIX1; KDM5B; KAT7; CTR9; ZBTB18; CCNA2; HMGN3; KDM2A; ZNF672; FOXO3; HMGA1; CHD9; SOX4; TBX3; TAF12; FLNA; RBBP4; DNAJC1; MAX; ZFHX4; AFF1; NCOR2; BANP; CITED2; HOXC6; NCOA4; RBBP7; CRY1; SIM2; MXD4; SAFB2; TWIST1; TCF4; HMGB3; ISL1; ZNF721; KLF5; CDK7; MTF2; ZMYM2; FOXJ3; TLE1; NFATC3; MNAT1; KAT6B; STAT1; NFIB; CHD1; SIX2; MAFF; CALR; HEY1; NR2F2; ATF5; NUP62; ESR1; MEIS1; ID4; BASP1
Down-regulation	70	ARNT2; VDR; SOX13; CEBPD; PRDM2; ZHX2; POLR3C; GMNN; TRIB3; LHX6; TAF4B; ACTL6A; SOX18; TFAP2C; KLF11; IRF6; NR1H2; TDP2; MYBL1; HIRA; FOXF2; KAT2B; IRF9; IFI16; PSMC3; THAP7; MBD2; YAP1; TCF21; HDAC9; ZNF232; RORA; ZNF467; ZNF589; KLF9; CBFA2T3; TERF1; RAD21; TFAP2A; MYRF; SUPT6H; HOXD1; AEBP1; BACH2; ZEB1; NEUROD1; ERBB4; NR5A2; ZKSCAN1; SRCAP; ZNF623; KDM5D; WT1; CEBPB; KLF10; GATA6; NR2F1; ZBED2; JUNB; HLF; TGFB1; ZFPM2; JUP; ZFP36L2; KLF4; SNAI2; CRK; EGR1; SMAD3; TCEA2