Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62062	Xylazine	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	ZNF189; KLF2; HMGA1; CTR9; CBX3; POLR2A; BRD8; KMT2A; ZHX3; BRIP1; PHF8; ZIC1; ING1; USP22; BRD3; TBL1X; TEAD1; SFPQ; ING3; MEF2A; TFAM; BRPF1; UBP1; BCLAF1; SMARCA4; BRCA1; RBM14; XBP1; RBPMS; HMG20A; TRIM28; MYCBP; MAGED1; BMI1; KDM4A; VEZF1; KAT7; LPIN2; MLX; TCF12; ZEB2; NKX3-1; CHD7; KLF5; ZKSCAN1; NRIP1; GTF2IRD1; PHF2; USF2; BCL10; CLOCK; SAP30; MAX; ZMIZ2; ZMYND11; REPIN1; BCL6; SMARCE1; MECOM; PATZ1; HLF; DEK; DNMT3B; PCGF2; SIX1; NR1D2; RBBP4; NUP62; CREB3L1; KDM2A; DNAJC1; TRIP6; HMGA2; ETV1; NFIB; NR2F2; ZZZ3; TRRAP; HNRNPD; BBX; TBPL1; MTF2; BAZ1B; TAF10; BASP1; SF1; EDF1; CHD9; SIX2; RBBP8; MNT; ZMYM2; HLTF; SREBF1; ZNF148; ATF1; SIAH2; NCOR2; CUX1; FOXJ3; DMTF1; ZNF160; STAT1; HDAC6; SMAD3; ZNF721; CRK; CHD1; IKBKAP; FLNA; TLE1; SOX9; DEAF1; NR4A1; NFATC3; EGR3
Down-regulation	76	ZNF215; IRF6; VDR; YBX3; CEBPD; ZNF345; NR0B1; ZNF133; NR1H2; ZNF544; ZNF83; OVOL2; PRDM2; ZNF688; NFE2; CERS4; THRB; PSMC3; ZNF682; JUN; HOXA4; ZNF165; TFAP2A; HLX; NR1H4; REL; BACH2; KLF11; CCNH; HOXB7; ZNF589; WT1; ZNF232; VPS72; ZSCAN31; SSBP3; TRIB3; TCEB2; PHIP; TCF21; ZNF264; CD3D; POU2AF1; PBXIP1; DLX2; ESR1; ARID5B; GATA6; ZNF426; TFDP2; HOXB2; SOX17; BNC2; SOHLH2; RBM39; ZNF467; PFDN5; HOXA5; ELF4; AEBP1; ZNF91; HOXC6; EMX2; NFATC4; MAF; WNT4; LMCD1; HMGB3; HHEX; TGIF1; BHLHE41; MXI1; ID1; MEIS1; TCEA2; EGR1