Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62045	Gw-5074	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	KDM5A; POLR2A; ELF2; ZNF652; TOB1; DNAJC1; BRD3; CTR9; USF2; BCLAF1; BCL3; ELK1; ORC2; SMAD5; EZH2; MED1; TCERG1; RERE; ARID4A; KDM2A; JARID2; PHF8; PRKDC; PITX1; BMI1; MLLT10; BRD8; SNIP1; NR2C1; ING1; RUVBL2; TRIM16; ZNF146; RFX5; PIR; SAP18; SUV39H1; VEZF1; KDM5B; SMARCA2; BATF; CHD3; ZNF384; SIX1; COPS5; ASH2L; MAGED1; MGA; EDF1; KAT7; MTA1; TBL1X; SFPQ; ZBTB18; CBX5; MAZ; WDHD1; LPIN2; PIAS2; MEF2A; FLNA; BRPF1; TRIM32; PSPC1; HDAC1; ZBTB11; FOXC1; IRF4; XBP1; ZMYND11; IRX5; MED6; ZMIZ2; RBBP4; ERBB2; FOXO3; NFKBIB; GTF2I; ZNF184; ZNF131; CITED1; KMT2A; HSF2; MYCBP; KMT2B; DNMT3B; TCF12; E2F8; RBM14; NEDD8; AFF1; PCBD1; TBP; SETD3; COPS2; HMGA2; HMGN3; ARID1A; TSC22D2; MAX; MDFI; CITED2; HNRNPD; ZMYM2; RBBP8; NR1D2; PIAS3; TBL1XR1; NR2F2; SOX9; CDK7; BCL6; NKX3-1; NONO; TCFL5; SIAH2; CRY1; HOXC6; ZIC1; HLTF; SMAD3; SIX2; RBPMS; MECOM; MSX1; TAF9B; FOXJ3; TSC22D1; SREBF1; NFATC3; MYB; DEAF1; HMG20B; TCF4; CHD1; ATF5; KAT6B; NUP62; TLE1; IKBKAP; ENO1; CRK; TCEA2; BASP1
Down-regulation	101	ARNT2; PAX5; ZNF331; GLI2; PTTG1; BACH2; HMGB2; GMNN; ZNF573; VDR; ZNF500; EN1; FOXI1; TRIB3; KLF11; PAWR; GATA1; LDB1; SOX13; ZNF268; HBP1; ZNF83; MLXIP; TFCP2L1; HDAC9; IRF8; CEBPD; TBX1; TDP2; ATOH1; IRF6; ZNF136; ZNF544; ZNF701; ERBB4; IRF1; ZNF264; ZNF350; KLF9; PRDM2; RORA; ZNF345; ZFP36L1; TOX; OVOL2; PSMC3; ZBTB20; MEOX2; ZNF91; KLF7; NR4A2; CDX1; NR3C2; NR1H2; ZNF112; TFAP2A; BNC2; SATB2; POU2AF1; ZNF195; IFI16; WT1; MEIS2; SPIB; ZEB1; ZNF623; KLF10; ELF4; SHOX2; CCNH; ZFPM2; ZNF93; TOX3; SNAI2; GATA6; BRD4; INSM1; TCF21; INSR; CREBL2; ZNF415; RNF138; ID3; FOXO1; EGR3; HEY1; ZMYND8; DACH1; WWP1; HOXA5; HOXD1; EMX2; ID1; PBX3; ZFP36L2; LOXL2; TGIF1; MAF; EGR2; ATF3; EGR1