Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61961	Securinine	GSE92742	NPC	Human	24h	10uM	EID0348

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	ELF2; SERTAD2; ETV5; PSPC1; MAGED1; HIRA; YAP1; ZNF184; HDAC1; ARID1A; SMAD6; ZNF107; DNAJC2; LEF1; SOX4; HOXC6; ERBB2; HMGN3; RREB1; MED1; SIM2; CARHSP1; FLNA; GATAD2A; PIAS3; SIX1; KMT2A; MTF2; CREB3L2; PBXIP1; MNAT1; ZMYM2; FOXJ3; TRIM16; CUX1; CDK7; CEBPB; TLE4; BIRC2; TOX3; ELF5; TBL1XR1; KAT6B; SOX9; HOXC10; CHD1; ID1; HDAC6; ASCL1; TLE1; HMG20B; NFATC3; HHEX; LOXL2; NR2F2; ID4; KDM5D
Down-regulation	41	ZNF835; PNRC1; MAFB; KLF9; HLX; KLF10; AEBP1; TFDP1; NAB1; FOXA1; ZNF331; IRF6; KLF11; ZNF423; NFKB1; ENY2; CREM; ESR1; MAF; KLF6; CCNH; RBPMS; KLF4; TRPS1; YWHAB; IFI16; FOSB; MAFF; HOXD1; ZFPM2; EGR3; ATF3; NR4A1; CRK; INSM1; PEG3; TCEA2; EGR1; ETV1; EED; SMAD3