Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61922	Pirenzepine	GSE92742	NPC	Human	24h	10uM	EID0347

Response Information :

Types	Number	Response transcription factors
Up-regulation	46	ZNF544; GATA2; RING1; GATA1; ZNF688; HIPK2; AIP; TCEB2; HOXC5; RXRA; SETD3; PRDM14; TCF21; KLF7; TSHZ2; MAFG; RFXANK; NR0B2; NFE2; CITED2; TWIST1; RBPJ; SOHLH2; CDIP1; TFDP2; BNC2; NKX2-1; TCF7L2; ATF4; RUVBL2; GTF3A; KLF6; PBX3; ZNF117; CALR; GABPB1; KDM5D; SCAND1; HMGB3; OSR2; IRF6; ETS1; EMX2; PEG3; TCEA2; CEBPB
Down-regulation	137	DMTF1; ATF1; XBP1; EHF; TLE1; USP22; RNF138; TOPORS; ZZZ3; NUP62; PSIP1; HMGA2; THAP1; RNF111; ZNF419; ZNF107; LHX1; HES1; ATF2; CRK; RBBP8; PHF2; ING2; ZNF468; ZBTB11; ZNF189; TTF2; MEOX1; PSMC3IP; NFYB; NPAS2; BRCA1; EED; BRIP1; ACTL6A; UBE2B; ITGB3BP; ZNF443; BBX; ZNF267; MED6; REST; KLF2; HDAC6; BMI1; CRY1; PAX5; CBFB; ZFX; NR1D2; CBX3; NFIB; TAF10; ZNF12; MED4; MEF2A; MAML1; MED7; NAB1; TMF1; PATZ1; CDK9; CREBL2; CHD1; DNAJC2; SMAD3; EGR3; CCNC; ZSCAN18; UBP1; AHR; FOSL2; HOXB13; SAFB2; SMAD4; DEK; SFPQ; TAF9; RNF6; ZNF148; SMAD6; KAT7; TERF2; HMGA1; TRIM22; REPIN1; TSC22D1; NKX3-1; ZMIZ2; SOX17; WWP1; ZBTB18; BCL10; EGR1; FHL2; CHD9; ERBB2; TFAM; ZNF329; IRF8; CTBP2; TOX; TFEC; HOXD1; ZNF217; POU4F1; NR2F1; SIX1; BIRC2; MBD2; TGFB1; ZBTB38; ZFP36L1; ELK3; TRIM16; SMARCA2; ZEB2; TRIM29; KAT2B; NR4A1; SMAD7; EGR2; ID3; ERBB4; LEF1; IKBKAP; ING3; ZIC1; SOX10; ETV1; BHLHE41; SNAI2; BASP1; MAFB; MAGED1; MYBL1; TRIB3