Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61875	Podophyllotoxin	GSE92742	NPC	Human	24h	10uM	EID0347

Response Information :

Types	Number	Response transcription factors
Up-regulation	157	FOSL1; MYC; LHX3; ATF3; CITED2; ABL1; AIP; ZNF93; GBX1; ZNF394; RARG; PROP1; NR0B2; ETV4; TP73; MAP3K10; HOXC8; SP100; CSDC2; MLXIP; ZFHX2; KLF15; CEBPE; HAND1; TUB; CREB3L2; HOXA6; KLF7; TFE3; HOXB1; HIPK2; IRF6; TWIST1; PRDM14; KLF6; PNRC1; ZNF91; ARID3B; ZNF253; SUPT3H; ZNF43; DRAP1; MAZ; ZFPM2; MAFF; LITAF; ZNF669; THAP4; PCGF1; AGO2; HOXA3; TCF21; TEAD3; HDAC5; CDX1; GFI1; SERTAD2; DDIT3; NFE2L2; HIRA; MAFG; HOXA4; PDLIM1; HDAC9; RELA; ZNF665; NFIC; CRTC1; TP53; ZNF85; CEBPD; ATN1; RNF10; HMGA1; HINFP; MED15; VGLL1; GATAD2A; RREB1; FHL2; PKNOX2; ETV6; ZNF384; MKL1; GLI3; MXI1; ETS1; ATF4; RBFOX2; NFRKB; NFE2; IRF5; ACTL6B; HHEX; TFAP2A; FOXJ2; LHX6; FOXO3; CDIP1; REL; MNAT1; PIR; BNC2; OSR2; SCMH1; PHF1; TCF7L1; EN1; ZBTB16; NKX2-1; KAT2B; SNAI1; MNDA; TGFB1I1; ZHX2; ZNF415; KLF4; FOXK2; JUND; NR1H4; JUN; FOXF2; JAK2; ZNF264; PTRF; ZNF44; FOSB; LYL1; PBX3; MYBL1; MECOM; PPP1R13L; FOXJ1; SOX13; KDM5C; BHLHE41; HOXD3; NR4A3; CBX4; FOXC1; BCL11A; AR; IFI16; PEG3; CEBPG; ELF4; KLF9; NR4A2; ZNF652; SATB2; HOXD1; TCEA2; SNAI2; CEBPB; TRIB3; ETV1; HOXA5
Down-regulation	216	EZH2; KAT6A; TFDP1; NUP62; PSIP1; FUBP1; ZMYM2; HES1; BRCA1; USP22; THAP1; TOPORS; HMG20A; CCNA2; CBX5; PARP1; ZNF432; ZNF267; ING1; HDAC6; NAB1; ZBTB11; TAF1D; BCOR; BCL6; GTF2I; UBTF; PUF60; NFIL3; NAB2; ATF1; ING2; WDHD1; EGR3; ETS2; ZNF302; BRIP1; SUV39H1; NRBF2; MTF2; BRD8; RBBP4; BCLAF1; UBE2I; CDK2; MYT1L; ZNF146; ZBTB18; ZBTB1; SMARCC2; MBD4; CBFB; CBX3; ZNF529; PHF2; BMI1; BAZ1B; TBL1XR1; TFAM; SREBF1; CENPB; HNRNPD; ZNF12; EED; SOX4; TRIM28; RBBP8; PATZ1; MED4; E2F6; RNF138; HMGN3; PKNOX1; ZFP30; PSPC1; ZNF443; TFCP2; TERF2; RFX5; TSC22D1; MAML1; MED1; RBL1; EDF1; PAX5; ISL1; SFPQ; SMARCA5; UBP1; ZBED1; CARHSP1; RCOR1; PRKDC; HMGB1; WWC1; CLOCK; ITGB3BP; DACH1; ZNF24; SMARCE1; TAF7; PBX1; NR1H3; ZBTB24; CENPF; NFIB; ZMIZ1; HMGB2; NONO; URI1; TBPL1; ZNF551; NCOA4; HEY1; SMARCA4; CCNE1; MED7; CHD1; ZNF510; SOX11; TBP; TGS1; NPM1; TDRD3; STAT1; ID3; DDX5; WWTR1; EGR2; LPIN2; BACH2; HOXB7; NLK; ADNP; ZKSCAN7; CUX1; PITX2; ZNF200; SIX1; SAP18; PBXIP1; TCF12; HLTF; LEF1; RFX7; SMARCA1; ZMYND11; ATF7IP; NCOA2; CHD8; MYCN; RNF6; NR2F1; ZBTB20; LIMD1; TERF1; ZNF281; TLE4; SMAD3; CRY1; MAGED1; NKX3-1; CREBZF; SOX2; NRIP1; ZNF226; PURA; ZIC1; SUB1; ZNF672; SMAD6; DNMT3B; RBBP7; ZSCAN18; HSF2; BBX; ZNF266; STAT4; MAFB; RBM14; KLF5; ZFP64; GLI2; RNF141; TRRAP; DEK; BCL3; HMGB3; SCAND1; RCOR3; ERBB2; PCGF2; ZMIZ2; PTTG1; TSC22D4; ZNF22; APEX1; CHD4; ID4; ZNF587; CUX2; RERE; EYA2; ZNF217; ASCL1; CITED1; KDM5D; HLF; HOXC6; CHD7; TOX; SAP30; STAT5B; IKBKAP; MYB; BASP1