Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61839	Aliskiren	GSE92742	NPC	Human	24h	10uM	EID0347

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	SMARCD2; GATA3; PPARD; GATA1; STAT3; NFKB2; PCGF2; ZNF335; CITED2; NOC2L; RFXANK; RXRA; HIRA; KMT2B; CASZ1; RUVBL2; PIR; TRIM28; MAX; HHEX; HDAC1; NFE2; LDB1; AR; SKI; CARHSP1; TAL1; HLX; DRAP1; DPF2; ARNTL; MMS19; DBP; EZH1; GRHL2; NKX2-2; TBL1X; TCEB2; TXNIP; TRIM32; TEAD3; PITX2; FOXO1; ETV5; CBFA2T3; KLF4; EDF1; TCF4; TFDP2; RBBP7; IRX5; NCOA3; DAXX; ABL1; ZNF331; MAF; KLF7; OSR2; SMARCD3; SOX9; IRF6; JUP; MNDA; KLF1; YWHAB; RORA; BHLHE41; AEBP1; EMX2; ESR1; CEBPB; CDK7; TCEA2
Down-regulation	173	CRK; GTF2A2; RFX5; CDK2; DMTF1; MEOX1; XBP1; RNF111; NUP62; ZFP69B; NFYB; ATF3; BCOR; HDAC9; XRCC6; BRIP1; ETS2; USP22; ZNF529; ZNF107; TOX3; HDAC6; DEK; TTF2; THAP10; ZNF419; E2F3; PATZ1; SMAD3; EED; ASCL1; CBX3; NR1I2; SHOX2; BRCA1; ZNF667; HES1; CBFB; NFIB; BMI1; NR1H3; TSG101; PSIP1; TFEC; ENY2; CREBL2; PRRX1; NPAT; NPAS2; ATF2; CNOT1; ATF1; HOXB13; SIX1; SALL2; ZNF267; PEX2; SIX2; TAF10; ZBTB11; PLAGL1; ZKSCAN7; TRIM22; HIF1A; GMNN; TDP2; NR1D2; DDX17; ZZZ3; PBX1; INSM1; ITGB3BP; RBFOX2; HSBP1; ZBED2; LPIN2; MAML1; NAB1; IFI16; TAF9; SUB1; ZNF443; YBX2; DNAJC2; TRPS1; UBE2B; FOSB; ZFHX3; NCOA2; ZSCAN18; ACTL6A; MSX1; HIPK1; EN1; HEY1; TMF1; EGR3; ZBTB38; HMGN3; ZKSCAN1; TDRD3; ZNF177; ZNF302; NR2F1; DLX2; MED13; ERG; MEIS1; ID3; HOXB2; ZNF266; HMGB2; YBX1; HOXD1; SMARCA2; KLF10; ZNF232; ZNF532; STAT6; TOB1; STAT1; PTRF; SMAD4; ZBTB18; LOXL2; FOSL2; RAD21; ZNF239; CTBP2; FHL2; PHF8; DDX5; NR5A2; TOX; ID1; TERF2; ZNF589; DACH1; TERF1; NKX3-1; ZNF195; NRIP1; ZEB1; ERBB2; MBD2; ASH2L; PTTG1; MYBL1; KDM5D; MEIS2; INSR; TFCP2L1; STAT4; SOX17; VDR; SAP30; NR4A1; SNAI2; HOXB6; ZNF131; CTR9; MYCL; BASP1; SMAD7; EGR2; PBX3; ETV1; NR2F2; VPS72; LEF1; EYA2; MYB; HOXA5