Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61722	Amlodipine	GSE92742	NPC	Human	24h	10uM	EID0347

Response Information :

Types	Number	Response transcription factors
Up-regulation	177	ZNF91; LHX3; FOS; EVX1; ZNF331; RING1; PNRC1; IRF6; MLXIP; NFATC4; HDAC5; ZNF688; PAX6; CALCOCO1; PROP1; STAT2; HIPK2; AIP; ZNF500; HBP1; CAMTA2; MXI1; REL; TWIST1; ZNF264; SRCAP; ZNF768; NR0B1; MAZ; NEUROD2; INSR; RFXANK; PRDM14; ZNF394; THRB; ZNF124; JUP; SATB2; KLF3; HSF4; SUPT3H; BARX1; CDX1; PFDN5; TP73; MYBL2; ZNF665; ACTL6B; CNOT3; TGFB1; NFE2L2; CERS6; MYBL1; IRF9; ZNF224; TLE2; CBX4; ZNF430; ZNF580; KDM4C; ZNF415; DDIT3; CITED2; PCGF1; CCNH; ZNF573; SMAD1; MED15; SNAI1; ING4; HIRA; TEAD3; ZHX2; KLF13; GFI1; ZNF215; ZNF611; SOHLH2; ZNF136; CXXC1; SHOX2; SPI1; TFAP2A; KLF7; INSM1; HLX; LHX6; TBX1; MED12; WNT4; LZTR1; VPS72; TULP3; BNC1; BCL11A; TSHZ2; CREM; CDIP1; EGR1; ZNF85; PHF1; EMX2; ZNF467; HDAC9; ID2; BTG1; VGLL1; ESR1; ERBB4; VDR; NR1H2; TCF7L2; NKX2-2; ZNF43; HOXB5; GCFC2; MYCL; ST18; RORA; FOXK2; RBM39; ZNF44; HHEX; CEBPD; PRDM2; ARID5B; CREB3L2; BRD2; ZNF165; SOX13; CBFA2T2; NFE2; MYRF; MED13; ATF6; KLF11; CALR; PBXIP1; CEBPB; PRDM12; ZKSCAN1; MEIS2; FLI1; KAT2B; DBP; HMGA1; ZNF652; OVOL2; GATA6; NEUROD1; NR4A3; HOXB2; BRD4; OSR2; BHLHE41; AES; CEBPG; ERG; ZNF423; POU2AF1; HOXC10; TXNIP; CTBP2; ZBTB16; KLF9; ZFP36L2; FOXG1; SNAI2; ZIC1; TCEA2; JUNB; TRIB3; SSBP2; ETS1; KAT6B; AEBP1; WT1
Down-regulation	235	EZH2; NUP62; RHOA; PSIP1; SPDEF; CBX3; THAP1; ZMYM2; ATF1; NFIL3; USP22; HNRNPD; CCNA2; PARP1; DR1; BMI1; NONO; CARM1; UBE2I; ING2; WDHD1; BRCA1; HMGN3; SMARCA4; NEDD8; CENPF; ZBTB11; HMG20A; SFPQ; SETD2; ETS2; CEBPZ; MED4; SMARCE1; SOX11; SUV39H1; NCOA4; RNF138; RBBP4; GABPA; KAT7; TLE4; NRBF2; REST; SMARCC1; RNF4; WWTR1; PATZ1; SUB1; ZNF189; PUF60; SPEN; EYA1; ECD; BAZ1B; ZNF146; UBP1; RNF111; PSMC3IP; BCLAF1; ENO1; ZNF84; ELF2; SP110; TFDP1; HMGB2; CNOT1; CBFB; TBP; NRIP1; ILF2; LPIN2; RBM14; ZBTB24; HDAC2; CHAF1B; CRK; DEK; JARID2; ZKSCAN7; TCERG1; HEY1; BCL10; EWSR1; YBX1; E2F3; PKNOX1; ZNF267; TRIM28; ID4; CRY1; RAN; TBL1X; RBL1; ZNF248; ERBB2; ZNF45; ING1; TAF11; TSC22D1; MAF; CBX5; SMARCA5; MED1; BRD3; BRIP1; PHF2; RNF6; ZNF764; ZMYND11; PCGF2; MLLT10; TEAD1; CREG1; WHSC1; SNW1; XRCC6; ZNF672; ZFP64; E2F6; SNIP1; HSF2; CENPB; TBX3; BIRC2; EGR3; BATF3; NELFB; BRD8; SP2; TFAM; DPF2; TRIM24; ELK1; FOXO1; ZNF443; HDAC6; ZNF184; HDAC1; USF2; URI1; DNMT3B; SF1; RFX7; DNAJC1; NPM1; ZBTB1; NKX3-1; TCF12; CHD1; NFE2L1; MSX1; EGR2; PLAGL2; REPIN1; STAT1; SMAD2; ASCL1; BATF; RBBP7; CTCF; PRKDC; LZTS1; ZNF552; ITGB3BP; SIX1; DDX5; PSPC1; MLX; APEX1; BACH1; ZBTB18; TRIM32; EDF1; SAP18; ATF7IP; NR2F1; MAGED1; ID3; VEZF1; MED7; EED; KDM2A; ZNF226; FOXF1; GLI2; CDK8; FLNA; RBBP8; HSBP1; TRRAP; MYCN; SREBF1; BAZ1A; ARL2BP; PRRX1; PBX1; ASH2L; ZNF131; ETV1; TRIM22; LEF1; RNF14; C1QBP; PIAS3; BBX; SMAD4; PTTG1; TOX; TDP2; MED24; LMCD1; NR2F2; HMGB3; IKBKAP; NR4A1; RBPMS; ZMIZ2; HLTF; ZEB1; CTR9; ZBTB38; NCOR2; CITED1; SMAD6; LOXL2; ZNF217; ZNF22; CDK7; STAT5B; EYA2; KDM5D; MYCBP; HOXC6; BASP1