Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61600	Guanfacine	GSE92742	ASC	Human	24h	10uM	EID0346

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	ZNF586; MTF2; PSMC3; ZNF444; ZNF419; ARNT2; ZNF12; ZNF430; NKX2-1; ZNF195; ZNF211; IRF9; ZNF304; LEF1; ZBTB44; ZNF91; ZEB1; ZNF43; GTF3A; NFE2; ZNF654; CD3D; ZNF264; ZNF124; ZNF273; TCF7; MYBL1; TOX; ZNF711; FOXG1; ZNF551; TRIB3; MKL2; TFAP2A; SALL2; TFDP2; ZNF134; HMGB1; KLF13; THAP4; ZNF107; CNOT3; KLF7; TEAD4; CDK2; HIC2; MYCL; ZNF665; ZNF544; ZBED2; DNMT1; ZBTB20; EGR2; SMAD1; SHOX2; ZNF587; MITF; ST18; EMX2; HIRA; HOXB2; TCEA1; ZBTB16; ERBB4; TSC22D1; ZKSCAN1; ZNF443; ATF3; NR3C2; MAZ; TRPS1; MYB; ESR1; TOX3; ID1; CBFA2T3; ZNF331; DACH1; EGR3
Down-regulation	55	TCEA2; KDM2A; BCLAF1; SMARCA2; PCGF2; EDF1; HIVEP1; XBP1; CREM; PHF2; HLTF; NRBF2; SF1; LMCD1; RUNX3; DDX5; TFDP1; BMI1; MEIS1; PURA; TULP4; TRAK1; CBFB; RFX5; WWTR1; ZBTB38; BATF; CENPF; FOXC1; HIPK3; TCERG1; ZEB2; PBX3; CSDE1; NKX2-2; NR2F2; PIR; HES1; TRIP6; DNAJC1; FOSL2; MAF; CITED2; SPEN; KLF9; GATA6; FLNA; NFIL3; NUP62; KDM5D; MAFB; IRF4; TRIM29; PBX1; BHLHE41