Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61598	Aliskiren	GSE92742	ASC	Human	24h	10uM	EID0346

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	NR3C1; MYBL2; IRF9; ARNT2; FOXE1; NKX2-1; NFATC4; TRIB3; ZNF117; ZNF232; JUN; PRDM2; CBX7; GMNN; ZNF74; POLR3C; ZNF224; ZNF444; RFXANK; PIAS4; THAP7; ABT1; ZNF91; ZNF557; RING1; SMARCB1; ZNF85; HOXB6; HBP1; ZNF350; RBFOX2; ZNF611; MYBL1; ZNF44; FOXF2; SCAI; CCNH; ZNF500; ZEB1; E2F4; SOX13; PCGF1; PFDN5; SALL2; CDK2; DNMT1; TOX; TEAD4; DEK; VPS72; SUMO1; MTF2; ATN1; SPDEF; HOXD1; TCEA1; FOXM1; ZNF711; TGIF2; HIRA; ZBED2; FOXJ3; MKL2; HOXB2; DAXX; TFAP2C; BCL11A; ATF3; TFAP2A; CTBP2; ELF4; HOXB5; PHIP; PROX1; NAB2; CD3D; CUX2; TULP3; HSF1; ZNF43; AEBP1; OVOL2; GRHL2; ZNF652; TAL1; ING4; RARG; WT1; ZNF124; HLX; ESR1; MED15; PAWR; ZNF544; CNOT3; OSR2; TCF7L2; TCF7L1; ZNF239; E2F8; CALR; HIC2; SUZ12; NEUROD1; RBPJ; ZNF589; ZNF665; ERBB4; DLX2; ZBTB16; ZNF160; IRF6; SSBP3; ZNF623; IFI16; BNC2; AES; AR; ZFPM2; CCNE1; CTBP1; SMAD1; TGFB1I1; ZFP36L1; MYCL; HEY1; MXI1; BACH2; TCF7; PBXIP1; ZNF573; PAX6; MEIS2; SHOX2; REL; ZNF264; CBFA2T3; MEOX1; ST18; FOXF1; GATA6; ID4; BHLHE41; HHEX; SOX11; CHD7; SOX17; TRPS1; INSR; ID3; MYB; NR2F1; LEF1
Down-regulation	131	KDM2A; STAT1; CTR9; ZNF672; AFF1; BHLHE40; HLTF; BCLAF1; IRF5; LMCD1; TSC22D3; NRIP1; EBF2; NRBF2; ZBTB38; TBP; SMAD2; PHF2; CEBPD; ADNP2; MSC; ZFP64; ZNF226; MED1; STAT5B; ZMYND11; BBX; EGR1; RNF141; SMARCA5; RBM14; RHOA; TMF1; PIAS3; NCOA6; SFPQ; MAGED1; ORC2; TULP4; SMARCA2; ZBTB1; ZEB2; KAT7; SIAH2; HOXA5; PIAS2; NFKB1; EP400; PAX8; BRPF1; STAT5A; EDF1; RNF6; HOXC6; STAT3; TOPORS; ASH2L; BATF3; ZBTB11; TRIM16; PCGF2; CNOT1; USF2; LIMD1; BMI1; BAZ1A; FOSL2; RUNX3; POLR2A; MYCBP; KLF2; CCNA2; EZH2; TFDP1; RNF10; TRIM28; ZNF783; ABL1; JARID2; TAF10; TBPL1; PIR; RFX5; PLAGL1; HMGA2; TADA3; CRY1; TCERG1; HTATIP2; ING3; MSX1; BTAF1; MAF; RB1; POU4F1; CREB3L1; BAZ2B; KDM5D; ARNTL; MED24; SF1; ZNF274; ZNF189; IKBKAP; DDX5; PSIP1; SMAD3; FOXC1; NCOA4; KLF6; HES1; PURA; SIX1; FOXD1; UBP1; EYA2; NUP62; SATB2; MED23; ZNF516; TXNIP; DNAJC1; YBX1; KLF10; ELK3; ZNF217; TRIM24; NFIL3; TRIP6; MNDA; RELB