Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61430	Pyrimethamine	GSE92742	ASC	Human	24h	10uM	EID0345

Response Information :

Types	Number	Response transcription factors
Up-regulation	78	MYCN; ZNF177; ZNF268; ZNF669; IFI16; ZNF44; CAMTA2; MKL1; ZNF257; ZNF573; ZNF223; PROX1; MYT1L; NKX2-2; NFE2L2; ZSCAN9; ZNF140; ZNF281; MED20; SOX13; TEAD3; ZNF222; MYBL2; INSM1; NR3C2; RBFOX2; BRD4; MEIS2; PEG3; ARID3B; E2F3; NR5A2; HOXA1; FOXO1; FOXE1; ERG; BNC2; COPS5; WT1; SNAI2; HLX; CUX2; ETS1; ZNF85; ZNF232; TWIST1; GATA6; PRDM2; ZMIZ1; IRF7; ZNF91; ETS2; ZNF165; NR1H2; ZNF430; ZNF264; DLX5; ZFPM2; SIN3B; ZNF43; TGFB1; ZNF117; HOXD1; VDR; ZIC1; SOX17; HIC2; ZEB1; HDAC9; ID4; PBX3; MEIS1; BCL11A; MAFB; CRK; ZNF512B; NR2F6; VPS72
Down-regulation	65	AR; MXD4; KMT2A; PSIP1; TSC22D3; MYCBP; RBBP4; HSBP1; CTNNB1; SOX9; SAP30; ZEB2; NR1H4; POU5F1B; PHF8; SIAH2; YBX3; NFKBIA; TSC22D1; ITGB3BP; FOXD1; KAT6B; HDAC1; EZH2; BHLHE41; IRX5; SREBF1; TBL1XR1; CSDE1; BCL6; TBL1X; EDF1; HSF2; TXNIP; FHL2; PIR; ZBTB18; KLF6; ERBB2; ELK1; MYRF; NR2F1; KLF2; NR2F2; NFKB1; DNAJC1; MYC; DMTF1; ZBTB20; TOX3; SMAD3; CITED2; TOB1; PAX5; KDM5D; HOXC6; HOXA10; NFKB2; CEBPZ; ID2; TP53; ZBTB38; EGR2; EGR1; TCEA2