Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61336	Rofecoxib	GSE92742	ASC	Human	24h	10uM	EID0345

Response Information :

Types	Number	Response transcription factors
Up-regulation	177	HDAC6; GATA3; HMGA2; CHD3; TRIM32; FOXA1; GATA4; CALCOCO1; FOXL2; NFIB; CASZ1; ZNF384; MZF1; NEUROD1; CUX1; NRIP1; ZNF408; ZNF629; HTATIP2; PAX3; IKBKAP; AR; TRAK1; TLE4; HDAC5; ATF7IP; TBX19; HOXD11; ELF2; FLI1; BARX2; MAML1; HMGN3; HOXB2; SMARCD1; HMBOX1; UIMC1; RXRB; TFEC; BTF3; KDM5D; FOSL2; NR2F2; EN2; MLLT10; CNOT2; KMT2B; SSBP3; ZNF226; RNF14; WWC1; FOXC1; SATB1; ZFY; MED6; SIAH2; MECOM; WNT4; NFIL3; HES1; POLR2A; ASXL1; RUNX3; HMG20B; RUVBL2; RHOA; CBX7; PCBD1; CIZ1; RNF10; PCGF3; SERTAD2; ZNF587; FOXJ2; MAF; PNRC1; PRMT2; IFI16; TTF1; BRPF1; ZNF589; ZNF394; IRX5; BCLAF1; CBX8; POU2AF1; DRAP1; DDX5; FOXN3; PBXIP1; SMAD1; SMARCA4; ZNF222; DNMT3B; REPIN1; HOXB5; YWHAB; HOXA5; HHEX; RFX5; ZNF516; MLX; STAT6; AES; USF2; SIRT7; ERG; TAF10; ELK1; CTBP1; NELFB; MEN1; CHD7; MED24; ATF1; MAX; SAFB2; ZMYND8; LEF1; PBX3; TCEA2; ZNF652; HDAC1; RNF6; PTTG1; PAX6; ZNF302; EDF1; FOXO3; ZNF227; CITED2; FOXD1; KAT7; ERBB2; TBX3; PCGF1; TEAD4; FOSL1; MED17; NFKBIA; CREB3L2; SIX2; TRIM28; JARID2; BCL3; HOXB6; RXRA; TAF1D; SSBP2; MAFB; HOXC10; SMARCD2; IRF7; PCGF2; PAX5; YBX3; HOXB7; BTG1; MEIS1; ZBTB16; MYC; TRIM16; IRF2; TRIP6; PEG3; MED1; ISL1; MED21; BPTF; MLXIP; ID2; ZSCAN18; TRIM22; MSX1; BASP1; FHL2; CRK
Down-regulation	155	PUF60; ZFP36L1; PEX2; PLAGL1; TOX3; APEX1; SMAD6; LOXL2; TAF1A; POU4F1; MEIS2; MYRF; TCEA1; NANOG; ZEB1; TRIM29; NR2F1; NCOA2; TERF1; CCNH; MTDH; RAD21; TCF25; MED14; MNDA; SKI; ZBED1; SKIL; SMARCA5; TGIF1; RBBP8; TGFB1; DACH1; TERF2; PBRM1; USP22; ETS1; HSF1; EGR3; TFDP1; ZNF239; TCF7L2; TAF1; ENY2; WDHD1; NR1D2; RBBP7; CBFB; KDM5C; CDYL; E2F3; SATB2; ETV4; COPS5; PRRX1; AGO2; NFATC3; HOXD1; SUZ12; NFATC4; CHD8; LDB1; BRD7; STAT4; ARNT2; ARID4A; TFAP2A; ZNF623; ATF2; BANP; RCOR3; ZNF215; TAF11; PAWR; RNF138; ID4; SP3; WWP1; ZNF423; HIF1A; TDP2; PRKDC; EHF; SIM2; SOX13; ZHX2; IRF1; PMS1; BRD4; SOX2; CEBPD; ZNF195; TAF4B; PSMC3; NR4A3; CRYM; TULP3; ARID5B; KLF5; UBE2B; POLR3C; CHD4; BHLHE41; SRCAP; ILF2; RYBP; CTBP2; ZFP36L2; MED20; HMGB2; ERBB4; CREB1; FOXJ1; EYA1; EYA2; DR1; SUPT3H; RFC1; TCF7; CREBL2; CDC5L; CBX3; ASCL1; ATF3; XBP1; PRPF6; EGR2; FOXG1; IRF8; ZNF430; ZNF217; RBPJ; MED13; ETV5; KLF11; FOXF1; GTF2IRD1; TCEB2; ST18; ZNF331; SP140L; TCF4; FLNA; GLI2; ZNF512B; MYB; ZBTB18; NFKB2; ID3; EMX2; HOXA10; NR4A1; CEBPZ; NR4A2; EGR1