Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61318	Thiotepa	GSE92742	ASC	Human	24h	10uM	EID0345

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	GATA2; PLAGL2; HHEX; FLI1; YEATS2; NFATC4; MECOM; SOHLH2; RSF1; HAND1; HEY2; AR; ALX1; AIP; SSBP3; PHIP; TAF1A; NFE2; ZNF250; IRF4; MED12; IRF1; KLF7; KLF5; MXD3; SOX17; PGR; ZNF257; PHF1; HDAC5; HOXC4; ZNF180; CCNH; HIPK2; ZNF235; HIVEP1; ZNF281; ZNF10; TAF4; ZNF232; BRF2; NR3C2; ING4; ZBTB1; IRF6; ZNF426; ZNF133; CDK2; PLAG1; MYCN; E2F8; HLX; SALL1; ASXL1; JUP; MEIS1; HIC2; NKRF; PRPF6; GMNN; ZNF74; ISL1; BNC2; MED21; ZNF302; PSMC3; HOXA11; ZNF623; CBFA2T2; TGIF2; WHSC1; NFE2L3; ZFPM2; ERG; SMARCA1; PNRC1; SPDEF; SALL2; PBX3; SNAI2; IFI16; MAFG; KAT2B; VDR; EMX2; TCEA2; PIR; AEBP1; CREB3L2; DDX17; MYBL1; HMGB3; LIN28A; TCEB2; TRIM29; NR4A3; RFC1; ZNF652; HTATIP2; ZNF43; MLXIP; GRHL2; MED17; YBX3; HIRA; TAL1; ELK3; KLF11; ZNF512B; PITX1; LEF1; TOB1; MITF; ID4; EYA2; ERBB4; ID1; ZNF331; NR4A2; NFKB2; ESR1; FHL2; VPS72; NR2F6
Down-regulation	131	TCF25; SOX9; TLE1; CDK9; SIX1; RBBP4; KLF9; SMAD2; PPARG; CBFB; ZNF146; BCOR; NR2F1; IRF8; EGR3; NFE2L1; TSC22D3; SHOX2; NUP62; PTRF; HNRNPD; APEX1; FOXJ3; VAX2; PAX5; MBD2; CNOT3; NPAS2; PCBD1; BASP1; BBX; POU2AF1; SPIB; RUNX3; BRD4; TSC22D1; RBBP5; XBP1; VGLL4; USP22; MAGED1; ITGB3BP; BAZ1B; ABL1; ZBED1; SAFB2; MTDH; AATF; TSC22D4; NONO; ZNF148; CENPB; ZNF432; FOXG1; SOX13; HEY1; ATF1; SAFB; NRBF2; ING2; ZIC1; ERBB2; CREB3L1; USF2; LOXL2; NCOA4; TRIM22; TFAM; ZNF24; KDM5D; C1QBP; ZMIZ2; SMARCD3; INSM1; SIX2; ZNF226; PCGF1; SF1; GTF2IRD1; PIAS2; MYRF; IKBKAP; ZNF419; BRD3; TRIM16; ZHX2; TGFB1; NCOR2; KLF2; EZH2; BMI1; ETV5; ZNF12; FOSB; CBX3; DNAJC2; AES; C1D; RERE; SMARCA2; SUB1; MEOX2; ZNF91; TCF7; TLE2; NR2F2; CITED1; TSC22D2; RYBP; BRD2; PSIP1; CHD9; TRIM28; ASCL1; ZMYM2; HOXA10; ZSCAN18; SMAD3; MED1; MYC; HOXA5; EGR2; JUND; TRIP6; SMARCD2; PPARD; CRK; ID2; TBL1X; TP53; EGR1