Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61277	Mexiletine	GSE92742	ASC	Human	24h	10uM	EID0345

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	TBX2; EP300; RLF; CREG1; PPARG; ZBTB1; ZNF32; ZNF354A; ZNF544; HAND1; NFE2; URI1; MECOM; NFE2L1; KLF6; GATA6; TWIST1; STAT1; ZNF165; ZNF180; ZFHX3; CENPF; ZFP64; ZNF131; COPS2; CREB3L2; MYCN; ZNF281; ZNF654; MTDH; STAT4; CCNE1; PMS1; HMBOX1; WT1; TADA3; NFE2L2; SREBF2; AHR; SUB1; HOXB5; SLC2A4RG; BAZ1A; SOX17; CUX1; ZNF410; SETD2; AFF1; TCEA2; MNDA; ERG; ELF4; MEIS1; IRF9; RFXANK; CHD1; ARID1A; MSX1; TCF7L2; TCF7L1; MEOX2; IRF7; TGFB1; BBX; HIRA; SOX11; CALR; HOXB7; KLF10; MITF; PIR; NR1H2; TOB1; EMX2; KLF2; STAT6; PBX3; ZNF512B; ID1; NR2F6
Down-regulation	76	RHOA; BCOR; MAFF; KLF9; SOX9; FOSL1; GON4L; FOXG1; YBX1; FOXA1; INSM1; CDK9; EN2; BTF3; HBP1; RBBP4; NKX2-1; IRF8; HLF; PARP1; TRIM29; TLE2; BRD8; ZBTB16; CDK8; UBE2I; ZNF528; GTF2I; EGR3; ST18; MNT; KDM5D; TCF7; LOXL2; CD3D; KAT6B; NCOR2; TCEA1; EZH1; CBFA2T3; BCL6; NR4A1; BHLHE41; MAGED1; PAX6; ATF3; NKX3-1; CREB3L1; FOSB; HOXC10; ELF3; TRIM28; ENO1; USP22; YBX3; TOX3; TULP3; SSX1; SERTAD2; ZBTB20; TFAP2C; ELF5; SOX10; FOXF1; TBX3; ZBTB18; TRPS1; NR2F1; MTA1; ID2; RBPMS; NFKB2; LEF1; TP53; CRK; EGR1