Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61261	Donepezil	GSE92742	ASC	Human	24h	10uM	EID0345

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	HOXD11; USP21; POU2AF1; ZNF354A; TOX; KLF5; FOXO1; EMX1; TONSL; NFKBIB; CDIP1; VGLL1; YEATS4; TSG101; PITX2; MYT1L; MAPK8IP1; ZNF165; CBX2; MYBL1; POU4F2; ZBED2; BAZ2A; POU4F1; NKX2-1; FOXE1; BARX1; TLX3; ZNF536; FLI1; NFATC3; TP73; ZNF556; RBBP8; NFYB; IRF4; ZNF571; FOXC1; URI1; TRIB3; HHEX; MYCL; SUZ12; ZNF835; ZNF232; BRIP1; MYBL2; NFE2L2; SOX13; POLR3C; SETDB1; CCNE1; SIX3; WT1; ZNF281; PBX3; ETS2; POU2F2; SUPT5H; KLF13; INSM1; MED13; IFI16; STAT4; RAD21; BNC1; TGS1; ARL2BP; BNC2; TAF5; CLOCK; SOHLH2; SUPT3H; NFE2L1; TGIF1; SMAD1; SKIL; VDR; SOX15; ST18; THAP1; TCF7L1; SOX2; TCF21; MYCN; ETS1; TOPORS; ILF2; PAWR; MEN1; AEBP1; ZNF329; CNOT6; TERF1; CDC5L; HLX; CBFA2T2; HOXD1; TFAP2A; ZSCAN18; MXI1; TCEA2; HOXA1; SSX1; GATA6; ACTL6A; NR1H2; HES1; ZNF131; DLX2; CREB1; SMARCC2; NFATC4; HOXA11; BBX; ERBB4; RNF138; ZKSCAN1; VEZF1; TULP3; VPS72; TP63; IRF6; HOXA5; RBPMS; CTBP2; TFAM; HOXB7; TFDP2; HOXA10; NCOA3; ATF3; NR2F6; ID1; CRK
Down-regulation	133	YBX1; HSBP1; RBBP4; FLNA; NPM1; UBE2I; NFIB; ZFHX4; GTF3A; SOX9; RAN; TCF7; MMS19; ZNF266; NR2F1; PAXBP1; PLAGL1; SND1; TRIM24; CREB3L1; NR2C1; HCFC1; ZNF226; NONO; ZMYND8; SP100; ERCC3; ZNF432; BHLHE41; ZEB1; CENPB; DDX17; TFEC; KAT8; CDYL; NCOR2; PCGF3; EMX2; ENO1; PUF60; LOXL2; TRPS1; SCAND1; RNF4; SMARCE1; DNAJC2; KAT6B; ZNF160; ZBTB20; MEIS1; TRIM28; RBBP7; CTNNB1; SP110; FOXJ3; SUV39H1; CEBPA; NFKBIA; ERBB2; SMARCD3; TFE3; SIRT7; ZNF587; HEY1; ZNF83; TBX3; EGR3; ZMIZ2; PSMD9; TCERG1; MED24; SALL1; RORA; ZNF93; TLE2; SPDEF; FOXD1; IRF8; FOSL1; JARID2; GTF2F1; STAT5A; XBP1; TRAK1; PCGF2; PHIP; MSX1; DNAJC1; DRAP1; NCOA4; SSBP2; ZNF721; CTBP1; ZMYM2; SP140L; HDAC1; KDM5D; SMARCA1; RUVBL2; MYC; MAGED1; DMTF1; RERE; NEDD8; TGFB1I1; SAP18; ZBTB18; MTA1; TRIM16; NR2F2; ELF5; MED1; KLF2; EZH2; ZNF274; EYA2; PITX1; ZMIZ1; ELK3; MAF; TP53; WWTR1; SMARCD2; FOSB; NFKB2; EGR2; ID2; ZNF331; CEBPZ; ESR1; BASP1; FHL2; EGR1