Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61183	Doxorubicin	GSE92742	ASC	Human	24h	10uM	EID0344

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	GABPB1; EPAS1; SOX2; ZNF654; CREB3L2; GATA2; ZBED2; KLF5; HCFC2; EED; EHF; IRF1; INSR; ILF2; RBBP8; RAD21; KLF13; ASCL1; RYBP; PBX1; NFATC3; CDIP1; SFMBT1; NHLH1; LITAF; EP300; PEG3; MEIS1; VDR; ZFHX3; LEF1; ZNF432; CCNT1; BCL10; ZNF3; PSPC1; ZNF573; ETS1; FOXJ3; ID3; IFI16; DR1; ZNF623; KAT2B; ZNF75D; TBX21; TAF5; MYBL1; NR5A2; ZNF562; KDM2A; HIPK2; YAP1; FOXO4; CREG1; HES1; ZNF24; ZNF232; MTDH; MED13; SOHLH2; NR1H3; HOXD1; GTF2A2; TBPL1; ZFP30; RARG; CBFA2T2; TCF21; NKX2-1; HMBOX1; L3MBTL1; BATF; MECOM; ZNF557; FUBP1; BPTF; HMGB3; HHEX; ZNF34; MED17; TRPS1; SMAD7; ID2; HEY1; MYCN; EZH2; ZNF606; KLF4; TP63; ZBTB32; ASXL1; EGR2; SNAI2; STAT1; IRF9; HLX; FOXA1; PEX2; NFKBIB; HOXB5; NFATC4; ITGB3BP; PBX3; CNOT6; GATA6; PTTG1; ZNF415; CALR; SOX11; SSX1; DACH1; CUX2; HAND1; BRD2; ZNF200; SP140; NFIC; GMNN; TWIST1; MYCL; TFEB; BATF3; TCF3; NEUROD1; ZNF665; GLI2; CBFA2T3; ID1; CHD7; ZNF281; TFAP2A; ZNF44; TCF7L2; BHLHE41; NR2F1; ZEB1; HBP1; ATF3; IRF4; ZFPM2; SMAD1; HMGB2; FOXF1; ZBTB20; ZNF331; TDRD3; CERS4; NFIB; WT1; WWTR1; SPEN; TBX3; CDK2; MYRF; KLF10; CD3D; ST18; ZNF721; YBX3; TOX3; MAFB
Down-regulation	157	BIRC2; MYC; CEBPA; MAGED1; STAT6; PSMD9; SNW1; PCBD1; SMARCD2; PPARG; RFXANK; PCGF2; JUND; PQBP1; FOSL1; SMARCC1; CEBPB; AATF; TLE1; NFE2L1; MLX; SCAND1; ECD; NONO; GATAD2A; UBE2I; FOSL2; DDX54; RBBP4; TCF25; MTA1; DEAF1; BAZ1B; SREBF1; MAZ; HNRNPD; DDIT3; HSF2; HDAC1; TRIM28; ZNF146; ZFP69B; PRKDC; ERBB2; HMGA1; REPIN1; CHAF1B; YBX1; MNAT1; PATZ1; ATF4; NPAS1; FOXO3; KLF2; HDGF; ZBTB25; GTF2IRD1; ZNF652; ZNF394; ZBED1; ASH2L; SUV39H1; CERS6; ZNF273; MITF; SMARCA4; TCF20; NFKBIA; XBP1; STAT5A; RUVBL1; FOXD1; ALX1; SAP30; SSRP1; KAT8; ELK1; PDLIM1; NCOA4; GFI1B; RREB1; CASZ1; USF2; MMS19; DNAJC2; BRD3; PHIP; TRIP6; CCDC59; ATF1; TBL1X; MED24; WDHD1; AES; TEAD4; BRD7; APEX1; SIN3B; CEBPG; KAT7; ERCC2; NELFB; BCLAF1; HOXC6; ZMIZ2; ZNF33B; IKBKAP; KDM5D; EYA2; TRIM32; LOXL2; KLF3; MED1; POU4F1; SAFB2; RBPMS; NCOR2; RUVBL2; TAF10; FLNA; PMF1; TSC22D1; PHF8; POU5F1B; TCERG1; SMAD3; NFE2; THAP11; NFE2L3; AEBP1; BTG1; ZNF226; CITED2; SIX1; MYT1L; ZNF117; HOXB7; KAT6A; NR2F2; DNMT3B; EGR3; GCFC2; SUB1; EDF1; KLF6; FOXC1; ENO1; TSC22D3; BCL11B; TCF7; PUF60; NKX3-1; HMGA2; YWHAB; DNMT1; PIR; EGR1