Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61097	Guanfacine	GSE92742	ASC	Human	24h	10uM	EID0344

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	PPARD; RFXANK; PBX1; MEIS1; PCGF1; CNOT2; YEATS4; ZNF219; NKX3-2; TLX1; CDIP1; TAF5; PIAS4; RING1; MXI1; RXRG; PHF1; SOHLH2; NKX2-2; CALR; HSF1; MTF2; ESRRG; PRDM10; DLX2; IKZF5; HEY2; FOXE1; ARID1A; ELK3; ZNF43; GLI3; IRF6; LITAF; FOXM1; AGO2; GMEB2; CCNT1; TEAD3; CNOT6; CARM1; TAF9B; PIAS1; PHIP; SATB1; CENPB; SMARCB1; IFI16; ZIC3; MTA1; RUNX3; ZNF580; NKX2-1; TWIST1; TGFB1I1; PBX3; BHLHE41; SSBP3; AES; MAFG; CEBPG; MED1; CITED1; ZFP36L2; BAZ1A; SALL2; FLNA; HHEX; TBX3; ZNF711; ZHX2; TRIP6; ZNF91; ZMIZ1; KAT6B; BATF3; ZFHX4; SOX11; VDR; SMAD1; IRF9; CDK2; ABL1; PIR; INSM1; RBPJ; MLXIP; IRF7; SERTAD2; HMGA1; TSC22D2; ZEB1; TRIM29; DNMT1; OSR2; HIC2; TCEA2; DACH1; AFF1; PUF60
Down-regulation	100	BCL6; USP22; TERF1; RBBP8; ZNF432; TAF7; NR4A1; ZSCAN18; ATF1; XBP1; MAGED1; EGR3; HLF; MAX; ASCL1; FOSB; ERBB4; ZNF248; ZNF419; TCEA1; PRRX1; MED4; TRIM22; ASH2L; RNF14; AHR; BRD8; ZEB2; CBX3; ID2; NR2F1; ZNF423; ZBED1; CREB1; KLF9; RRN3; NFE2L1; SMAD7; RAN; ATF3; BNC2; UBP1; CHD9; SMAD2; BRD4; EMX2; ING2; ARL2BP; ITGB3BP; ZBTB16; AEBP1; TSC22D1; NRIP1; BCLAF1; HMGN3; PPARG; KLF2; KLF4; ENO1; PPARGC1A; MYT1L; RNF6; PHF20; HOXD1; BMI1; HSBP1; CREBL2; TRRAP; LEF1; SMARCD3; NLK; HOXA10; ID4; KLF10; ETS2; HMGB3; ZNF532; DMTF1; ZBTB20; SIAH2; PLAGL1; SPEN; NPAS2; RBPMS; ZFPM2; SMAD6; TOX3; MEOX2; TOB1; MEOX1; GATA6; EGR2; ZNF217; TGIF1; TSC22D3; SNAI2; IRF8; EGR1; HMGA2; ZIC1