Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61094	Chlorambucil	GSE92742	ASC	Human	24h	10uM	EID0344

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	GABPB1; POU2AF1; MTF2; PRDM12; VDR; TCF4; NCOA1; ZSCAN9; NFATC3; CREB3; ARID3B; HLX; ERG; ZNF24; SOX2; DLX5; ZBED2; RAD21; PIAS4; ZNF232; SOX18; RYBP; MECOM; SOX17; SOX5; ZNF468; ACTL6A; RBBP8; ETS1; FOXG1; YEATS4; IRF6; CNOT6; INSM1; CREB3L2; IFI16; PRRX1; ZNF43; PSMC3; HIPK2; ZFHX3; MEIS1; KLF13; PBX1; SOHLH2; CCNE1; SMAD1; ZNF165; SERTAD2; SUPT7L; MDM2; SNAI2; ETS2; CEBPG; NFKBIB; NEUROD1; TFEC; ZNF83; FOXO1; SUPT3H; ATF3; NR5A2; TFAP2A; ZNF415; ANKRD1; HIC2; VGLL1; NR1H2; ZIC3; INSR; ZMIZ1; NKX2-1; CRY1; HEY2; EN1; DACH1; SOX13; TAL1; TCF7L2; MEOX2; ESR1; NFYB; TRPS1; IRF9; TWIST1; HTATIP2; ZFPM2; ZNF281; HOXB7; NAB1; IRX5; NFIB; NR1D2; ZFP36L2; GATA6; PEG3; VPS72; BCL11A; ST18; SHOX2; WT1; TCEA2; MAFB; DNMT1; FHL2; MSX1
Down-regulation	125	BIRC2; USP22; TCF25; HDAC1; FLNA; YBX1; MAGED1; TFE3; MAZ; UBE2I; NONO; ZNF358; HSF2; KDM4A; TBL1X; THRA; CEBPA; SCMH1; BAZ1B; TRIM28; ZMIZ2; MYC; TRIM16; SNW1; LOXL2; ZNF248; ZNF148; ZNF84; ZBTB24; MMS19; ZNF587; PCGF2; MED24; SREBF1; RBBP4; BAZ1A; NR2F2; NR2F1; ELK1; NFYC; SSRP1; DNAJC2; YAP1; STAT6; ATF1; ZNF580; TBP; RUNX3; STAT5A; RBBP7; ID3; RBPMS; BCL3; SMARCA4; ZNF329; GTF2IRD1; JUNB; ZZZ3; ZNF226; TCEB2; LDB1; SOX9; KAT7; CARHSP1; FOXD1; REPIN1; CSDE1; TAF7; BCLAF1; ZSCAN18; ATF7IP; PHF8; HLF; NFIC; NFE2L1; LITAF; SALL1; TRIM32; KDM5D; HLTF; CREG1; ZNF217; TP53; CREB3L1; ERBB2; ISL1; HOXC10; SIRT7; TXNIP; SOX10; PHF20; TADA3; EYA1; TCF7; ZNF189; SREBF2; ELF3; TRRAP; TLE4; THAP11; MYRF; DEAF1; BTAF1; EGR3; ZBTB18; PNRC1; TOX3; NKX3-1; HNRNPD; TCERG1; SAP18; FOXC1; CBFB; TOB1; OSR2; ZNF652; EZH2; IRF8; HEY1; SPIB; ZBTB38; HMGA2; CITED2; EGR1; EGR2