Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61091	Proguanil	GSE92742	ASC	Human	24h	10uM	EID0344

Response Information :

Types	Number	Response transcription factors
Up-regulation	82	MEF2C; NFATC4; KLF11; IRF6; EPAS1; XRCC6; MTF2; ARID5A; ATN1; FOXN3; SAP130; TBX1; TULP3; NR4A2; ZNF331; ZNF43; TCF20; MGA; GTF3A; IRF9; ZNF93; ARID5B; ARID1A; RORC; SSBP3; SMARCC2; ZNF117; ZNF512B; ZNF589; HEY2; NFKB2; CBX7; ZEB1; CALCOCO1; TCF7L2; TP63; YAP1; ZNF85; PSMC3; RUNX1; CHD8; HLF; PRPF6; CALR; MYCL; TGFB1; NCOA2; CREB3L2; ZFP36L2; PHIP; ZNF665; ZNF430; ZNF91; TFCP2L1; KLF13; RORA; THAP7; REL; ZFPM2; PBX3; TGIF2; GMNN; HIC2; HHEX; TRIB3; BHLHE41; SMAD1; CBFA2T3; MYBL1; HOXB2; TRIM29; NKX2-1; KLF6; FOXO1; TCEA2; ZBTB38; YBX3; ELF5; VPS72; ZBTB16; SHOX2; PUF60
Down-regulation	83	TMF1; ASCL1; BLZF1; ZNF432; TSC22D4; ZNF576; ZNF562; SKIL; ATF1; HLTF; ZNF205; PTTG1; THAP1; ZEB2; BBX; SMAD7; ZNF146; ZNF468; NR2F1; ING2; MAGED1; TAF7; USP22; ZNF410; SIX2; MNAT1; MLX; BAZ1A; RBBP7; PHF8; HOXC6; LITAF; UBP1; NCOA4; CRY1; RUVBL2; MYT1; ZNF302; RNF10; HES1; IRF4; MXD4; TP53; ZNF189; CCDC59; CITED1; ID1; ERBB2; TRIM16; TSC22D3; JARID2; NRIP1; KLF2; ISL1; NR2F2; RNF6; SOX15; MYCBP; PITX1; SIM2; INSM1; HSBP1; C1QBP; MBD2; HOXA5; TERF2; TFEC; TSC22D1; EZH2; BTG1; DNMT1; PEG3; TOB1; FOXD1; KDM5D; HMGA2; PIR; IRF8; NFIL3; BASP1; EGR1; MAFB; FHL2