Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61025	Mexiletine	GSE92742	ASC	Human	24h	10uM	EID0344

Response Information :

Types	Number	Response transcription factors
Up-regulation	62	PBX1; TCF12; CALR; SUPT4H1; DDX17; ZNF444; ZSCAN31; RYBP; IKBKAP; MED13; NAB1; BRD2; INSR; KAT6B; ZBED2; ZNF692; ERBB4; TGFB1I1; PAX6; MXI1; MEIS2; ZNF580; ZNF224; ZEB1; ZNF83; MYCL; INSM1; CHD7; NEUROD1; EGR3; SOX11; TSC22D2; DACH1; KLF13; ZNF177; ELF5; HHEX; ZNF91; BTG1; FOXA1; KLF7; TOX3; ZFPM2; TBX3; CERS4; ZBTB18; PEG3; ZFP36L1; TAL1; WT1; EGR2; ID1; ST18; CITED2; EGR1; ESR1; ZBTB16; SHOX2; BASP1; NFIL3; PUF60; FHL2
Down-regulation	62	SIX2; USP22; MKL2; PIAS3; SNW1; ATF1; RCOR3; DLX5; LITAF; ZNF423; ARNT; HLTF; HOXC10; TRIM22; MED6; CENPF; FOXC1; BAZ1A; ZNF468; TSC22D1; RRN3; FLI1; KLF2; HMGN3; HTATIP2; SMARCA2; ZEB2; TERF2; NR1D2; CTBP2; NEDD8; CRY1; TXNIP; ARL2BP; ERG; IRF7; GTF2I; CTR9; RUNX3; RBBP4; BCL11B; ETS2; THAP11; VDR; TDRD3; STAT1; FOXD1; ERBB2; PITX1; DNMT1; DNMT3B; MYBL1; SIX1; TSC22D3; FOSB; TCEA2; JUN; HOXC6; SOX9; HMGA2; IRF8; NFKB2