Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID61009	Donepezil	GSE92742	ASC	Human	24h	10uM	EID0344

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	MEF2C; MTF2; ILF2; RBBP8; FOXE1; FOXJ2; TCF4; TULP3; ARID1A; JUND; RREB1; HHEX; CRYM; MYBL1; NFE2L2; SOX17; BRD4; HEY2; TBL1X; PCGF1; COPS2; PBX1; ZNF443; FOXG1; FOXM1; CLOCK; KLF13; ZNF512B; ZNF232; TRIB3; ZNF354A; CTBP2; ZNF544; TCF7L1; ZNF43; IRF6; ZNF12; MGA; ERG; SMARCB1; ZNF665; AEBP1; ZFP36L2; POLR3C; TFCP2; KAT6B; CHD8; SMAD1; PAXBP1; NKX2-1; NCOA6; ZNF85; PHIP; DLX5; MTA1; E2F8; NR3C2; MECOM; SMARCA5; FOXO1; GMNN; DACH1; CCNE1; TFEC; ERBB4; CREB3L2; ZNF165; FOXI1; ZHX2; PSMC3; SETDB1; SLC2A4RG; HIC2; HIRA; NFE2L3; MYRF; HMGB2; SOX11; HBP1; SP3; CDK2; ID1; ZFPM2; VDR; PBX3; DNMT1; TCEA2; TRIP6; ESR1; SOX9; CITED2; VPS72; MYBL2
Down-regulation	60	YBX1; LITAF; SMAD7; INSM1; UBE2I; RXRA; SIX2; KDM5D; ZNF432; KAT2B; ZNF226; MMS19; ENO1; FLNA; HIVEP1; RBL2; ASCL1; TRIM29; MED24; ITGB3BP; BTAF1; ZBTB1; ZEB2; TRIM32; FOXD1; ATF1; TBPL1; JARID2; BATF; HOXB9; PTTG1; HLTF; ATF4; BATF3; MED21; MXD4; TP53; TXNIP; IRF1; HOXA10; MYCBP; BCL3; NR4A1; PEX2; EGR3; CREB3L1; RNF10; CHD3; HES1; TBL1XR1; BTG1; MSC; PITX1; HOXC6; KLF10; ZBTB38; BASP1; ZIC1; HMGA2; EGR1