Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60759	Donepezil	GSE92742	ASC	Human	24h	10uM	EID0343

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	PPARD; SOX2; SMAD7; ECD; TCF7L1; EGR1; SOX4; ELF5; FOXA2; NFE2L2; ARID4B; KDM5D; FOS; BATF; LYL1; ZBTB44; PFDN5; HHEX; SMARCB1; ELF1; NAB2; HOXA11; NFATC1; PAX5; GFI1; SMAD6; PIAS2; ZNF107; DNAJC2; TCEB2; MAFB; CCNE1; FOXE1; ETV1; TGFB1; ZSCAN18; POU2AF1; TBL1XR1; ZSCAN31; ZNF580; TGIF1; TSC22D2; MBD2; ZBTB18; HMGA2; ARID4A; CARHSP1; CRYM; BACH2; ZNF274; SALL2; HMGB2; BAZ1A; SOX10; POU4F1; JARID2; ZNF468; ST18; HIC2; MAGED1; PLAGL1; LMCD1; TCF7L2; CALR; IL16; DLX5; MYRF; NKX2-1; CBFA2T3; FOXD1; ZBTB20; ZHX2; AFF1; HEY1; GATA2; ISL1; PARP1; TLE4; TCERG1; ZIC1; TLE1
Down-regulation	68	IRF7; KLF6; WT1; NFYA; CERS6; PSIP1; IRF1; PBX3; MEIS1; CRK; ZFHX4; ZKSCAN1; MNT; ESR1; HMBOX1; TDP2; ZNF224; ATF3; BRD4; MEIS2; CBX3; TAF1; MAFF; TBL1X; ZNF44; STAT3; TFAP2A; URI1; ARNTL2; SP100; DACH1; ZMYND8; SNAI2; SMARCA2; PTRF; RORA; TGFB1I1; TRIM29; ZEB1; EMX2; ACTL6A; RBBP5; ZNF589; KLF10; SMARCA1; CTR9; BHLHE41; MYCL; PRKDC; TRIM16; ABL1; HOXB2; ZNF331; PRPF6; ZBTB38; TBX3; ID2; HOXB7; ID1; ZNF160; SATB2; NUP62; PIR; HLTF; ZNF91; ZNF551; NR4A2; NFKB2