Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60642	Isotretinoin	GSE92742	SKB	Human	24h	10uM	EID0342

Response Information :

Types	Number	Response transcription factors
Up-regulation	160	JAK2; FOXE1; PRDM10; RAD21; TCF7L2; MEIS2; NCOA2; COPS5; NFE2; MEOX1; TAL1; POLR3C; TERF1; UBE3A; TRIM33; TGS1; BNC1; GFI1B; CDC5L; PAXBP1; NR5A2; ID4; BHLHE41; HMGXB4; POU4F2; ELF4; SP2; TAF4; TCEA1; SRY; SPIB; ERBB4; SUPT4H1; MYB; VGLL1; SOX3; BACH1; TAF5; ST18; TTF2; GRHL2; ZBED2; SUPT7L; TFAP2A; ZNF10; PLAGL1; MED14; TOB1; PHIP; VEZF1; GATA1; TAF4B; ZFPM2; ZNF235; ZNF334; ZBED4; IFI16; ZNF175; EGR4; MYBL2; SSX1; CCNH; RNF138; RBPMS; THAP1; SSX3; HIRA; HIC2; ENY2; ELF2; ZNF239; ZNF492; SOX9; ZNF165; TFEC; CBFA2T2; KLF1; TAF5L; ZNF589; THAP10; E2F2; MKL2; HOXA1; MYCN; FUBP1; RBBP8; SP140L; KAT2B; NR1H4; TOX; NFE2L3; CDK2; TAF11; HOXD1; ZNF257; E2F8; HDAC9; RLF; WDR77; TCF21; GATA6; ADNP2; MYBL1; TGIF1; NFIB; ZBTB20; TRIB3; ELF5; ARL2BP; TWIST1; PAWR; MED17; TFDP2; CBFA2T3; ZNF180; NANOG; ATF3; HHEX; NR1H2; ZNF350; RFX5; KLF10; IRF9; TGFB1I1; PAX6; DACH1; CUX2; CAMTA1; HMGB2; MNDA; TRIM22; LMCD1; SOX10; NR3C2; RNF6; WWC1; NEUROD1; MAFB; HOXB7; IRF1; KAT6B; CREB3L2; FOXM1; TDP2; LITAF; BIRC2; SUB1; DNMT1; EGR2; IRF6; EHF; MEIS1; ZNF331; TCF4; ZNF217; GMNN; PEG3; ARNT2; WT1; ZNF91
Down-regulation	195	PUF60; SMARCD2; ATF5; NELFB; ERCC2; MBD3; FLNA; ZNF358; CRK; DEAF1; TRIM28; TCF25; TAF10; PARP1; KMT2B; MMS19; ZBTB48; PPARD; RELB; MDFI; FOSL2; SSRP1; RHOA; SND1; USF2; HDAC7; ATF7IP; POLR2A; ZNF646; CASZ1; TRIM16; NUP62; HSBP1; XBP1; RARA; MAGED1; NFKBIA; MDM2; FOSL1; MLXIPL; ZNF629; CARM1; TP53; SREBF1; APBB1; CHD8; SIRT2; BRD4; TSC22D4; SIX2; NCOR2; MYOG; NCOA4; POU5F1B; TRAK1; WIZ; PITX2; TBL1X; ZNF783; MED1; ZKSCAN5; SIX1; RXRB; SMARCC1; RUVBL2; KAT5; CERS6; PBRM1; MXD4; MED16; CNOT1; ZNF189; ENO1; HIVEP2; SF1; SLC2A4RG; HLX; NFE2L1; HOXA11; EDF1; GTF2IRD1; HDAC11; ZNF205; SMARCA1; EPAS1; ATF6; PATZ1; INSR; ETV1; ZMIZ2; FOXD1; BCL3; CHD3; CIC; MTF1; TSC22D3; TSG101; GATA4; ZNF672; RORA; MED7; BTG1; CXXC1; MEF2A; AES; NEDD8; TCF15; SIAH2; CREB3L1; PCGF2; ELK3; PIAS3; CENPB; SMARCA4; ZFHX4; TRIP6; ELK1; RBPJ; PBXIP1; PRPF6; ZMYND8; TRIM27; ZKSCAN1; MED6; TOX3; MAF; RNF10; BATF3; ATF4; CUX1; NFKB1; BRPF1; MED24; PA2G4; NR2F2; TFDP1; KLF7; KDM5B; BRD3; HMGB3; UBE2I; ZBED1; MEF2C; ZNF516; WWTR1; CENPF; ASXL1; MAZ; TAF6; HIPK3; CALR; ID2; SMARCE1; YBX1; HDAC6; ZIC1; ERBB2; BMI1; TXNIP; CTNNB1; HMGA1; MNT; RUNX1; IRX5; KDM5D; ZBTB38; FOXO3; CSDE1; CREM; ZBTB18; SMARCD3; AATF; EGR1; NFE2L2; TGFB1; DNAJC1; SKI; NR2F6; PBX3; ASCL1; MSX1; HOXC6; DNMT3B; STAT3; SIM2; HLTF; CITED2; PLAG1; HOXC10; SPDEF; EMX2; HMGA2; MNAT1; EGR3; FOXC1