Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60593	Withaferin-a	GSE92742	SKB	Human	24h	10uM	EID0342

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	KDM5A; FOS; EGR1; NR4A1; JUNB; MAFF; TCF7L2; PPARD; ECD; GFI1; MEIS2; ETS1; FOSL1; FOSB; BAZ2A; ID2; EGR4; VDR; MTF2; COPS5; SUZ12; NAB2; ID3; KLF13; RELB; SAFB2; NCOA2; PSMC3; SAP130; ID4; CD3D; SIX2; ERF; CTNNB1; SP140L; PQBP1; TWIST1; NR4A2; ZNF7; CBX4; SP2; ZNF200; SIX3; SNAI1; ATF3; ZNF394; DLX2; NFAT5; JAK2; ERBB4; EGR3; ZNF593; ARID3A; MED17; UBE2B; DR1; RBBP8; POLR3C; SALL2; HOXA5; ZNF410; NR5A2; CTBP2; FOSL2; ETV5; MED13; ELF4; CHD1; MBD2; FOXO4; ZNF423; SPIB; TOB1; SAP30; TTF2; KAT2B; MYRF; DMTF1; HSF1; TERF1; MNDA; DDIT3; REL; RXRA; IRF4; WDR77; ZNF467; ZFPM2; HLF; ZNF430; FLI1; ZNF432; EZH2; KLF10; TOX3; FOXL2; TFAP2A; AATF; STAT4; HOXB6; KLF2; TLE4; TBPL1; NR0B1; MYBL1; HOXA1; ZNF557; EGR2; BATF3; SSX1; TBX3; CITED2; HOXC4; MYB; DLX5; NKX2-1; ZNF267; WT1; HOXD11; HHEX; HES1; ZNF165; BATF; MXI1; PEG3; TAL1; ID1; SMAD6; BTG1; TP63; HOXD1; TOX; ZEB2; ZNF331; GATA2; TRIM24; HOXC6; AFF1; ZNF586
Down-regulation	107	MYC; ATF5; NELFB; CTBP1; NUP62; PUF60; TRIM16; ZBTB14; GTF2I; DNMT3B; MAF; SMARCD2; KAT6A; NFKBIA; RBPJ; PAXBP1; SCMH1; SMARCE1; RNF4; POU5F1B; SHOX2; ZBED4; ZIC1; MED24; CBX3; ZNF302; CREG1; TADA3; HDAC1; CENPF; PARP1; TRAK1; ZMYND11; HOXC13; REST; BRD3; ZNF83; CARM1; BRCA1; SREBF1; BMI1; ELK3; AHR; NLK; NFKB1; NCOA4; TLE2; MED23; FOXF1; ZMYND8; RBPMS; KDM5B; NFYC; KLF4; LIN28A; EDF1; SMAD1; ZFP64; LHX2; CCNA2; INSR; MTDH; RBL2; ERG; GRHL2; SUB1; NCOR2; NFIB; CEBPZ; DDX5; ZBTB38; BCLAF1; ETS2; SOX11; TRIM29; SMARCA5; NAB1; EYA2; YWHAB; OSR2; MNT; ZNF211; PAX6; NKX2-2; ZNF443; GTF3A; WWTR1; BHLHE41; SMARCD3; HEY1; POU2AF1; HLTF; IRF8; STAT3; NPAS2; LHX6; TRIP6; SCAND1; CBFA2T3; FOXC1; IFI16; TCF4; BCL11A; KDM5D; TSC22D2; MAFB; ZBTB18