Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60555	Motesanib	GSE92742	SKB	Human	24h	10uM	EID0342

Response Information :

Types	Number	Response transcription factors
Up-regulation	187	TCF7L2; SUZ12; LHX3; INSR; RFXANK; TFDP2; FOXE1; FOXO4; THAP3; NKX3-2; HEY2; HSF4; JAK2; NOC2L; HOXA5; MXI1; KDM5C; PBX3; E4F1; CCNE1; NFATC4; MEIS2; RUVBL1; GFI1; ZNF444; SIX3; E2F6; FOXF2; PROP1; ZNF500; GATA6; PHF1; PRDM12; ZNF215; PDLIM1; FLI1; BARX1; PIAS4; SOX13; HMX1; PSMC3; DLX2; PRPF6; NKX2-1; TGIF2; PHIP; ZNF232; TRPS1; PRDM10; SOX3; TP73; MYOG; ZNF93; SALL2; TFAP2A; GATA4; GLI3; CERS4; ZNF671; RXRA; UBE2I; MYBL2; NFIC; BRD7; ZNF711; TCF7L1; PBXIP1; VPS72; ZNF589; ZNF219; ZNF580; ERBB4; ZNF235; KLF13; MYCN; SUPT3H; SOX18; CD3D; SOX21; HIPK2; MYB; TRIB3; E2F4; CSDC2; HBP1; MLXIP; IRF6; WNT4; OSR2; CXXC1; HDGF; SRY; FOXK2; AIP; HSF1; DLX4; BACH2; TTF2; NR5A2; RBM39; NFKBIA; SUPT4H1; PGR; DMRT1; FOXO3; HHEX; ZNF552; ST18; TBX2; AATF; E2F8; ZKSCAN8; TBX3; ZNF467; NFE2; BRD4; TOX; HDAC4; CNOT6; RING1; NCOA2; PAX6; PRDM2; ZIC3; PFDN5; BTG1; ZFP36L2; UBE2L3; WDR77; EN1; DDX17; AEBP1; DLX5; MYRF; ZMYND8; TFAP2C; NR1H4; KLF11; HOXB5; CSDE1; MEF2C; STAT5B; ATF3; ZBED2; ARID3B; SOHLH2; HMGB3; BCL11A; ZNF165; WWC1; TAL1; SPIB; ZFPM2; DDIT3; HOXC8; HIRA; HIC2; TWIST1; RFX2; MTA1; STAT5A; ID1; NR2F6; HOXD11; HAND1; CTBP2; TCEA2; ATN1; KAT2B; CITED2; WT1; HOXD3; SALL1; CDK2; JUND; ARNT2; SPDEF; ZNF331; HOXB6; NFE2L3; ZNF91; SMAD6; SCAND1; MNAT1; ZNF586; POU2AF1; MYBL1
Down-regulation	220	XBP1; USP22; NUP62; DNAJC2; CRK; MYC; TOPORS; UBP1; REST; IKBKAP; HIF1A; TERF2; STAT1; CBX3; CREB3L1; ATF1; TRIM16; RBPMS; CLOCK; BASP1; JUNB; ZNF226; TADA3; RB1; MED4; PPARG; ZNF189; ZNF468; BMI1; SFPQ; FOXJ3; NRBF2; ZNF84; GTF2IRD1; PLAGL1; TSC22D3; HIVEP2; BAZ1A; C1D; MYCBP; TLE1; ZBTB11; CTR9; TFCP2L1; CCDC59; TMF1; CHD3; SNW1; ZNF146; RBBP5; ZFP30; NR2F2; ZNF329; KAT7; ATF7IP; PRMT2; BCOR; NKX3-1; PCBD1; HSBP1; SNIP1; RCOR1; ZNF160; CRY1; MED6; PIAS3; PKNOX1; NR4A1; CBFB; RRN3; MTDH; EED; ZBTB38; YBX1; GTF2I; ZMYND11; BAZ1B; TRIM32; ARNT; TOB1; ZBTB1; NRIP1; ZFP64; SAFB2; NCOA4; POU5F1B; CREB3; RNF6; ZZZ3; SCMH1; HOXA10; NFAT5; ORC2; MAGED1; PHF2; ZNF23; CHD9; MITF; TRIM22; PMF1; PATZ1; ZBED4; RBM14; COPS2; NR3C1; ATF2; ITGB3BP; RLF; KDM5D; JARID2; ZKSCAN1; RNF138; MDM2; TDRD3; ZNF721; NEDD8; SMAD3; NPM1; BCLAF1; ZNF432; FOXA1; SMAD5; ACTL6A; ETS2; ETV1; RYBP; TOX3; HIVEP1; HOXB13; SMAD7; EGR3; CCNA2; ZNF44; SMARCA2; MSC; ZBTB24; TGFB1; ADNP; GLI2; BCL11B; ZNF443; HDAC6; USF2; EGR1; ING1; CRYM; TXNIP; CREB5; SNAI2; PMS1; THAP1; ZNF606; SMAD2; CDK8; PHF20; TFAM; ZNF529; IKZF5; ZMYM2; IRF8; HMGA2; NR1D2; NFIB; EHF; BIRC2; TSC22D1; ZNF12; ARID4A; SATB2; RBL2; HLTF; PIR; ZNF131; KLF2; ZNF267; REPIN1; HOXC6; THAP10; IRF7; RORA; ID2; KLF10; ING3; FOXD1; SIX1; ZNF587; RNF141; SAP18; APEX1; TRIM28; HOXC10; TBPL1; ELK3; MEOX2; MEF2A; ZNF430; MNDA; ELF3; MBD2; TRIM24; STAT3; WWTR1; BHLHE41; MAFB; TBL1X; ERG; CREG1; ZNF217; NFATC3; NR3C2; MSX1; EGR2; BCL6; ASCL1; MECOM; LEF1; ZNF274; HTATIP2; PURA; GATA2